Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus

Abstract One mechanism of pollution resistance in marine populations is through transgenerational plasticity, whereby offspring capacity to resist pollution reflects parental exposure history. Our study aimed to establish correlations between oxidative stress biomarkers and key reproductive fitness...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kathryn N. Lister, Miles D. Lamare, David J. Burritt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/51ad201e26934e6b8d2a509d569ae9e5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:51ad201e26934e6b8d2a509d569ae9e5
record_format	dspace
spelling	oai:doaj.org-article:51ad201e26934e6b8d2a509d569ae9e52021-12-02T16:07:04ZMaternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus10.1038/s41598-017-02077-52045-2322https://doaj.org/article/51ad201e26934e6b8d2a509d569ae9e52017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02077-5https://doaj.org/toc/2045-2322Abstract One mechanism of pollution resistance in marine populations is through transgenerational plasticity, whereby offspring capacity to resist pollution reflects parental exposure history. Our study aimed to establish correlations between oxidative stress biomarkers and key reproductive fitness parameters in the temperate sea urchin Evechinus chloroticus following exposure to dietary polycyclic aromatic hydrocarbons (PAHs). PAH-exposed adults exhibited total gonad tissue concentrations of PAHs in excess of 4 and 5 times baseline levels, for females and males respectively. Antioxidant enzymes were upregulated and oxidative lipid and protein damage to gonad tissues occurred. In addition, early stage offspring reflected maternal antioxidant status, with progeny derived from exposed females demonstrating significantly higher baselines than those derived from control females. Maternal exposure history enhanced the capacity of embryos to minimise oxidative damage to lipids and proteins following exposure to additional PAHs, but provided less of an advantage in protection against oxidative DNA damage. Abnormal embryonic development was largely independent of oxidative damage, remaining high in all embryo populations regardless of parental PAH-history. Overall, results document evidence for maternal transfer of antioxidant potential in E. chloroticus, but imply that a short-term inherited resilience against oxidative stress may not necessarily translate to a fitness or survival gain.Kathryn N. ListerMiles D. LamareDavid J. BurrittNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kathryn N. Lister Miles D. Lamare David J. Burritt Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
description	Abstract One mechanism of pollution resistance in marine populations is through transgenerational plasticity, whereby offspring capacity to resist pollution reflects parental exposure history. Our study aimed to establish correlations between oxidative stress biomarkers and key reproductive fitness parameters in the temperate sea urchin Evechinus chloroticus following exposure to dietary polycyclic aromatic hydrocarbons (PAHs). PAH-exposed adults exhibited total gonad tissue concentrations of PAHs in excess of 4 and 5 times baseline levels, for females and males respectively. Antioxidant enzymes were upregulated and oxidative lipid and protein damage to gonad tissues occurred. In addition, early stage offspring reflected maternal antioxidant status, with progeny derived from exposed females demonstrating significantly higher baselines than those derived from control females. Maternal exposure history enhanced the capacity of embryos to minimise oxidative damage to lipids and proteins following exposure to additional PAHs, but provided less of an advantage in protection against oxidative DNA damage. Abnormal embryonic development was largely independent of oxidative damage, remaining high in all embryo populations regardless of parental PAH-history. Overall, results document evidence for maternal transfer of antioxidant potential in E. chloroticus, but imply that a short-term inherited resilience against oxidative stress may not necessarily translate to a fitness or survival gain.
format	article
author	Kathryn N. Lister Miles D. Lamare David J. Burritt
author_facet	Kathryn N. Lister Miles D. Lamare David J. Burritt
author_sort	Kathryn N. Lister
title	Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
title_short	Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
title_full	Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
title_fullStr	Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
title_full_unstemmed	Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus
title_sort	maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin evechinus chloroticus
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/51ad201e26934e6b8d2a509d569ae9e5
work_keys_str_mv	AT kathrynnlister maternalantioxidantprovisioningmitigatespollutantinducedoxidativedamageinembryosofthetemperateseaurchinevechinuschloroticus AT milesdlamare maternalantioxidantprovisioningmitigatespollutantinducedoxidativedamageinembryosofthetemperateseaurchinevechinuschloroticus AT davidjburritt maternalantioxidantprovisioningmitigatespollutantinducedoxidativedamageinembryosofthetemperateseaurchinevechinuschloroticus
_version_	1718384774873088000

Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus

Ejemplares similares