Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis

Abstract Some patients with idiopathic pulmonary fibrosis (IPF) require hospitalization due to pneumonia. Although predictive scoring tools have been developed and validated for community-acquired pneumonia (CAP), their usefulness in IPF is unknown. The Confusion, Urea, Respiratory Rate, Blood Press...

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Autores principales:	Ryo Yamazaki, Osamu Nishiyama, Kazuya Yoshikawa, Sho Saeki, Hiroyuki Sano, Takashi Iwanaga, Yuji Tohda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/51af558a9e9943ffa3c31a4ee8941afa
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spelling	oai:doaj.org-article:51af558a9e9943ffa3c31a4ee8941afa2021-12-02T14:03:44ZComparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis10.1038/s41598-021-83381-z2045-2322https://doaj.org/article/51af558a9e9943ffa3c31a4ee8941afa2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83381-zhttps://doaj.org/toc/2045-2322Abstract Some patients with idiopathic pulmonary fibrosis (IPF) require hospitalization due to pneumonia. Although predictive scoring tools have been developed and validated for community-acquired pneumonia (CAP), their usefulness in IPF is unknown. The Confusion, Urea, Respiratory Rate, Blood Pressure and Age (CURB-65) score and the Pneumonia Severity Index (PSI) are validated for CAP. The quick Sequential Organ Failure Assessment (qSOFA) is also reported to be useful. The aim of this study was to investigate the ability of these tools to predict pneumonia mortality among hospitalized patients with IPF. A total of 79 patients with IPF and pneumonia were hospitalized for the first time between January 2008 and December 2017. The hospital mortality rate was 15.1%. A univariate logistic regression analysis revealed that the CURB-65 (odds ratio 4.04, 95% confidence interval 1.60–10.2, p = 0.003), PSI (4.00, 1.48–10.7, 0.006), and qSOFA (5.00, 1.44–1.72, 0.01) scores were significantly associated with hospital mortality. There was no statistically significant difference between the three receiver operating characteristic curves (0.712, 0.736, and 0.692, respectively). The CURB-65, PSI, and qSOFA are useful tools for predicting pneumonia mortality among hospitalized patients with IPF. Because of its simplicity, the qSOFA may be most suitable for early assessment.Ryo YamazakiOsamu NishiyamaKazuya YoshikawaSho SaekiHiroyuki SanoTakashi IwanagaYuji TohdaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ryo Yamazaki Osamu Nishiyama Kazuya Yoshikawa Sho Saeki Hiroyuki Sano Takashi Iwanaga Yuji Tohda Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
description	Abstract Some patients with idiopathic pulmonary fibrosis (IPF) require hospitalization due to pneumonia. Although predictive scoring tools have been developed and validated for community-acquired pneumonia (CAP), their usefulness in IPF is unknown. The Confusion, Urea, Respiratory Rate, Blood Pressure and Age (CURB-65) score and the Pneumonia Severity Index (PSI) are validated for CAP. The quick Sequential Organ Failure Assessment (qSOFA) is also reported to be useful. The aim of this study was to investigate the ability of these tools to predict pneumonia mortality among hospitalized patients with IPF. A total of 79 patients with IPF and pneumonia were hospitalized for the first time between January 2008 and December 2017. The hospital mortality rate was 15.1%. A univariate logistic regression analysis revealed that the CURB-65 (odds ratio 4.04, 95% confidence interval 1.60–10.2, p = 0.003), PSI (4.00, 1.48–10.7, 0.006), and qSOFA (5.00, 1.44–1.72, 0.01) scores were significantly associated with hospital mortality. There was no statistically significant difference between the three receiver operating characteristic curves (0.712, 0.736, and 0.692, respectively). The CURB-65, PSI, and qSOFA are useful tools for predicting pneumonia mortality among hospitalized patients with IPF. Because of its simplicity, the qSOFA may be most suitable for early assessment.
format	article
author	Ryo Yamazaki Osamu Nishiyama Kazuya Yoshikawa Sho Saeki Hiroyuki Sano Takashi Iwanaga Yuji Tohda
author_facet	Ryo Yamazaki Osamu Nishiyama Kazuya Yoshikawa Sho Saeki Hiroyuki Sano Takashi Iwanaga Yuji Tohda
author_sort	Ryo Yamazaki
title	Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
title_short	Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
title_full	Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
title_fullStr	Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
title_full_unstemmed	Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
title_sort	comparison of curb-65, psi, and qsofa for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/51af558a9e9943ffa3c31a4ee8941afa
work_keys_str_mv	AT ryoyamazaki comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT osamunishiyama comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT kazuyayoshikawa comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT shosaeki comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT hiroyukisano comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT takashiiwanaga comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis AT yujitohda comparisonofcurb65psiandqsofaforpredictingpneumoniamortalityinpatientswithidiopathicpulmonaryfibrosis
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Comparison of CURB-65, PSI, and qSOFA for predicting pneumonia mortality in patients with idiopathic pulmonary fibrosis

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