Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis

Mudit Chowdhary,1 Ahmad A Kabbani,1 Devon Tobey,1 Thomas D Hope2 1Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA; 2Department of Neurology, Mercer University School of Medicine, Macon, GA, USA Abstract: Posterior reversible encephalopathy syndrome (PRES) is a...

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Autores principales:	Chowdhary M, Kabbani AA, Tobey D, Hope TD
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/51b1bf504cd043558f5f93536411f4ce
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spelling	oai:doaj.org-article:51b1bf504cd043558f5f93536411f4ce2021-12-02T01:11:57ZPosterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis1178-2021https://doaj.org/article/51b1bf504cd043558f5f93536411f4ce2015-04-01T00:00:00Zhttp://www.dovepress.com/posterior-reversible-encephalopathy-syndrome-in-a-woman-with-focal-seg-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Mudit Chowdhary,1 Ahmad A Kabbani,1 Devon Tobey,1 Thomas D Hope2 1Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA; 2Department of Neurology, Mercer University School of Medicine, Macon, GA, USA Abstract: Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome characterized by reversible vasogenic edema in the posterior hemispheres. PRES is most often attributed to primary hypertension, pre-eclampsia, and neurotoxicity secondary to immunosuppressants such as cyclosporine. Renal disease is an infrequent cause of PRES with a majority of cases occurring in adults with complete renal failure or in pediatric cases with underlying renal parenchymal disease and concurrent immunosuppressive therapy. Typical symptoms include seizure, headache, altered mental status, and visual disturbances. PRES is rarely associated with cerebral hemorrhage, and even less so with subarachnoid bleeds. Herein we report on a 25-year-old female with focal segmental glomerulosclerosis who developed PRES. The patient’s presentation was more severe as she presented with seizure, nephrotic syndrome, and subarachnoid hemorrhage. Computed tomography and magnetic resonance imaging with concurrent symptoms led us to the final diagnosis. The patient was treated with antihypertensives, diuretics, and corticosteroids and follow-up imaging revealed resolution of PRES. Our case illustrates that underlying kidney disease even without immunosuppressive agents should be added to the list of possible causes for PRES. Symptoms are reversible with treatment of underlying cause or offending agent. Keywords: PRES, posterior reversible encephalopathy syndrome, focal segmental glomerulosclerosis, subarachnoid hemorrhageChowdhary MKabbani AATobey DHope TDDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 1111-1114 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Chowdhary M Kabbani AA Tobey D Hope TD Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
description	Mudit Chowdhary,1 Ahmad A Kabbani,1 Devon Tobey,1 Thomas D Hope2 1Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA; 2Department of Neurology, Mercer University School of Medicine, Macon, GA, USA Abstract: Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome characterized by reversible vasogenic edema in the posterior hemispheres. PRES is most often attributed to primary hypertension, pre-eclampsia, and neurotoxicity secondary to immunosuppressants such as cyclosporine. Renal disease is an infrequent cause of PRES with a majority of cases occurring in adults with complete renal failure or in pediatric cases with underlying renal parenchymal disease and concurrent immunosuppressive therapy. Typical symptoms include seizure, headache, altered mental status, and visual disturbances. PRES is rarely associated with cerebral hemorrhage, and even less so with subarachnoid bleeds. Herein we report on a 25-year-old female with focal segmental glomerulosclerosis who developed PRES. The patient’s presentation was more severe as she presented with seizure, nephrotic syndrome, and subarachnoid hemorrhage. Computed tomography and magnetic resonance imaging with concurrent symptoms led us to the final diagnosis. The patient was treated with antihypertensives, diuretics, and corticosteroids and follow-up imaging revealed resolution of PRES. Our case illustrates that underlying kidney disease even without immunosuppressive agents should be added to the list of possible causes for PRES. Symptoms are reversible with treatment of underlying cause or offending agent. Keywords: PRES, posterior reversible encephalopathy syndrome, focal segmental glomerulosclerosis, subarachnoid hemorrhage
format	article
author	Chowdhary M Kabbani AA Tobey D Hope TD
author_facet	Chowdhary M Kabbani AA Tobey D Hope TD
author_sort	Chowdhary M
title	Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
title_short	Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
title_full	Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
title_fullStr	Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
title_full_unstemmed	Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
title_sort	posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/51b1bf504cd043558f5f93536411f4ce
work_keys_str_mv	AT chowdharym posteriorreversibleencephalopathysyndromeinawomanwithfocalsegmentalglomerulosclerosis AT kabbaniaa posteriorreversibleencephalopathysyndromeinawomanwithfocalsegmentalglomerulosclerosis AT tobeyd posteriorreversibleencephalopathysyndromeinawomanwithfocalsegmentalglomerulosclerosis AT hopetd posteriorreversibleencephalopathysyndromeinawomanwithfocalsegmentalglomerulosclerosis
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Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis

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