Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models
Summary: The translation of chimeric antigen receptor (CAR) T cell therapy for pediatric solid tumors is limited by the lack of preclinical models that fully recapitulate solid tumor biology. We describe steps to implement neuroblastoma metastatic and orthotopic mouse models. We delineate an analysi...
Guardado en:
Autores principales: | Nan Li, Rosa Nguyen, Carol J. Thiele, Mitchell Ho |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/51b45698cd264ae3a0c1ea891efc33b3 |
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