Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump

Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump

Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB protomers is functionally independent from the trimer...

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Autores principales: Chih-Chia Su, Linxiang Yin, Nitin Kumar, Lei Dai, Abhijith Radhakrishnan, Jani Reddy Bolla, Hsiang-Ting Lei, Tsung-Han Chou, Jared A. Delmar, Kanagalaghatta R. Rajashankar, Qijing Zhang, Yeon-Kyun Shin, Edward W. Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/51b9ec914f01445795f1807120926c42
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Sumario:Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB protomers is functionally independent from the trimer.

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