Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump

Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB protomers is functionally independent from the trimer...

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Autores principales:	Chih-Chia Su, Linxiang Yin, Nitin Kumar, Lei Dai, Abhijith Radhakrishnan, Jani Reddy Bolla, Hsiang-Ting Lei, Tsung-Han Chou, Jared A. Delmar, Kanagalaghatta R. Rajashankar, Qijing Zhang, Yeon-Kyun Shin, Edward W. Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/51b9ec914f01445795f1807120926c42
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spelling	oai:doaj.org-article:51b9ec914f01445795f1807120926c422021-12-02T14:16:14ZStructures and transport dynamics of a Campylobacter jejuni multidrug efflux pump10.1038/s41467-017-00217-z2041-1723https://doaj.org/article/51b9ec914f01445795f1807120926c422017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00217-zhttps://doaj.org/toc/2041-1723Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB protomers is functionally independent from the trimer.Chih-Chia SuLinxiang YinNitin KumarLei DaiAbhijith RadhakrishnanJani Reddy BollaHsiang-Ting LeiTsung-Han ChouJared A. DelmarKanagalaghatta R. RajashankarQijing ZhangYeon-Kyun ShinEdward W. YuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chih-Chia Su Linxiang Yin Nitin Kumar Lei Dai Abhijith Radhakrishnan Jani Reddy Bolla Hsiang-Ting Lei Tsung-Han Chou Jared A. Delmar Kanagalaghatta R. Rajashankar Qijing Zhang Yeon-Kyun Shin Edward W. Yu Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
description	Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB protomers is functionally independent from the trimer.
format	article
author	Chih-Chia Su Linxiang Yin Nitin Kumar Lei Dai Abhijith Radhakrishnan Jani Reddy Bolla Hsiang-Ting Lei Tsung-Han Chou Jared A. Delmar Kanagalaghatta R. Rajashankar Qijing Zhang Yeon-Kyun Shin Edward W. Yu
author_facet	Chih-Chia Su Linxiang Yin Nitin Kumar Lei Dai Abhijith Radhakrishnan Jani Reddy Bolla Hsiang-Ting Lei Tsung-Han Chou Jared A. Delmar Kanagalaghatta R. Rajashankar Qijing Zhang Yeon-Kyun Shin Edward W. Yu
author_sort	Chih-Chia Su
title	Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
title_short	Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
title_full	Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
title_fullStr	Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
title_full_unstemmed	Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
title_sort	structures and transport dynamics of a campylobacter jejuni multidrug efflux pump
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/51b9ec914f01445795f1807120926c42
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Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump

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