Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters

Wastewater contains a wealth of information about the inhabitants of cities. Wastewater-based epidemiology (WBE) has become an effective tool for monitoring public health by analyzing various biomarkers (e.g., chemicals and microorganisms) in wastewater. This way, the estimation of pharmaceuticals&#...

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Autores principales: Michal Bodík, Tomáš Mackuľak, Miroslav Feher, Andrea Vojs Staňová, Kateřina Grabicová, Dóra Varjúová, Igor Bodík
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Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/51bbcbabc24e4275a201dd03ff3dcb90
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spelling oai:doaj.org-article:51bbcbabc24e4275a201dd03ff3dcb902021-11-16T04:09:06ZSearching for the correlations between the use of different groups of pharmaceuticals from wastewaters0147-651310.1016/j.ecoenv.2021.112973https://doaj.org/article/51bbcbabc24e4275a201dd03ff3dcb902021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S014765132101085Xhttps://doaj.org/toc/0147-6513Wastewater contains a wealth of information about the inhabitants of cities. Wastewater-based epidemiology (WBE) has become an effective tool for monitoring public health by analyzing various biomarkers (e.g., chemicals and microorganisms) in wastewater. This way, the estimation of pharmaceuticals' consumption behavior and/or illicit drugs can be calculated. However, monitoring consumption alone is not the only option. If we consider wastewater as a statistical representation of the population's health, medical information can be derived. In this work, we used data from 15 different wastewater treatment plants in Slovak Republic to explore correlations between the use of typical pharmaceuticals and illicit drugs. The analysis was based on the wastewater monitoring data from four years (2016–2019), and 68 different compounds were taken into account. One of the strongest correlations found was between Antihyperlipidemics and Antihypertensives, with Pearson's correlation coefficient of 0.82. This type of analysis within the WBE represents a new potential as an additional source of information for the pharmaceutical, medical and government sectors in assessing health risk factors in the population. Such an evaluation method has even a great potential for artificial intelligence and machine learning for calculating health risk factors together with other sources of data.Michal BodíkTomáš MackuľakMiroslav FeherAndrea Vojs StaňováKateřina GrabicováDóra VarjúováIgor BodíkElsevierarticleWastewater-based epidemiologyDrug abusePharmaceutical consumptionPearson's correlation coefficientEnvironmental pollutionTD172-193.5Environmental sciencesGE1-350ENEcotoxicology and Environmental Safety, Vol 228, Iss , Pp 112973- (2021)
institution DOAJ
collection DOAJ
language EN
topic Wastewater-based epidemiology
Drug abuse
Pharmaceutical consumption
Pearson's correlation coefficient
Environmental pollution
TD172-193.5
Environmental sciences
GE1-350
spellingShingle Wastewater-based epidemiology
Drug abuse
Pharmaceutical consumption
Pearson's correlation coefficient
Environmental pollution
TD172-193.5
Environmental sciences
GE1-350
Michal Bodík
Tomáš Mackuľak
Miroslav Feher
Andrea Vojs Staňová
Kateřina Grabicová
Dóra Varjúová
Igor Bodík
Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
description Wastewater contains a wealth of information about the inhabitants of cities. Wastewater-based epidemiology (WBE) has become an effective tool for monitoring public health by analyzing various biomarkers (e.g., chemicals and microorganisms) in wastewater. This way, the estimation of pharmaceuticals' consumption behavior and/or illicit drugs can be calculated. However, monitoring consumption alone is not the only option. If we consider wastewater as a statistical representation of the population's health, medical information can be derived. In this work, we used data from 15 different wastewater treatment plants in Slovak Republic to explore correlations between the use of typical pharmaceuticals and illicit drugs. The analysis was based on the wastewater monitoring data from four years (2016–2019), and 68 different compounds were taken into account. One of the strongest correlations found was between Antihyperlipidemics and Antihypertensives, with Pearson's correlation coefficient of 0.82. This type of analysis within the WBE represents a new potential as an additional source of information for the pharmaceutical, medical and government sectors in assessing health risk factors in the population. Such an evaluation method has even a great potential for artificial intelligence and machine learning for calculating health risk factors together with other sources of data.
format article
author Michal Bodík
Tomáš Mackuľak
Miroslav Feher
Andrea Vojs Staňová
Kateřina Grabicová
Dóra Varjúová
Igor Bodík
author_facet Michal Bodík
Tomáš Mackuľak
Miroslav Feher
Andrea Vojs Staňová
Kateřina Grabicová
Dóra Varjúová
Igor Bodík
author_sort Michal Bodík
title Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
title_short Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
title_full Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
title_fullStr Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
title_full_unstemmed Searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
title_sort searching for the correlations between the use of different groups of pharmaceuticals from wastewaters
publisher Elsevier
publishDate 2021
url https://doaj.org/article/51bbcbabc24e4275a201dd03ff3dcb90
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