Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay
Our understanding of cytosolic delivery is hindered by existing methods for quantification which suffer from being indirect and showing low sensitivity. Here the authors report a SLEEQ (Split Luciferase Endosomal Escape Quantification) assay to assess cytosolic delivery of cell-penetrating peptides.
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Autores principales: | Serena L. Y. Teo, Joshua J. Rennick, Daniel Yuen, Hareth Al-Wassiti, Angus P. R. Johnston, Colin W. Pouton |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/51c2a8863f7b4866907c4bcbaa87460c |
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