RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities

The yeast and human RNA exosome is structurally related to prokaryotic phosphorylases but degrades RNA only via associated hydrolytic activities. Here the authors show that the RNA exosome of plants, and likely those of a few basal eukaryotes, combines phosphorolytic and hydrolytic activities to deg...

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Autores principales:	Natalia Sikorska, Hélène Zuber, Anthony Gobert, Heike Lange, Dominique Gagliardi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/51c593e8312846f39ddf67f4b16c3b38
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spelling	oai:doaj.org-article:51c593e8312846f39ddf67f4b16c3b382021-12-02T15:39:00ZRNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities10.1038/s41467-017-02066-22041-1723https://doaj.org/article/51c593e8312846f39ddf67f4b16c3b382017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02066-2https://doaj.org/toc/2041-1723The yeast and human RNA exosome is structurally related to prokaryotic phosphorylases but degrades RNA only via associated hydrolytic activities. Here the authors show that the RNA exosome of plants, and likely those of a few basal eukaryotes, combines phosphorolytic and hydrolytic activities to degrade RNA.Natalia SikorskaHélène ZuberAnthony GobertHeike LangeDominique GagliardiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Natalia Sikorska Hélène Zuber Anthony Gobert Heike Lange Dominique Gagliardi RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
description	The yeast and human RNA exosome is structurally related to prokaryotic phosphorylases but degrades RNA only via associated hydrolytic activities. Here the authors show that the RNA exosome of plants, and likely those of a few basal eukaryotes, combines phosphorolytic and hydrolytic activities to degrade RNA.
format	article
author	Natalia Sikorska Hélène Zuber Anthony Gobert Heike Lange Dominique Gagliardi
author_facet	Natalia Sikorska Hélène Zuber Anthony Gobert Heike Lange Dominique Gagliardi
author_sort	Natalia Sikorska
title	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
title_short	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
title_full	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
title_fullStr	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
title_full_unstemmed	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
title_sort	rna degradation by the plant rna exosome involves both phosphorolytic and hydrolytic activities
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/51c593e8312846f39ddf67f4b16c3b38
work_keys_str_mv	AT nataliasikorska rnadegradationbytheplantrnaexosomeinvolvesbothphosphorolyticandhydrolyticactivities AT helenezuber rnadegradationbytheplantrnaexosomeinvolvesbothphosphorolyticandhydrolyticactivities AT anthonygobert rnadegradationbytheplantrnaexosomeinvolvesbothphosphorolyticandhydrolyticactivities AT heikelange rnadegradationbytheplantrnaexosomeinvolvesbothphosphorolyticandhydrolyticactivities AT dominiquegagliardi rnadegradationbytheplantrnaexosomeinvolvesbothphosphorolyticandhydrolyticactivities
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RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities

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