Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano

Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequenc...

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Autores principales: Jakub Wudarski, Daniil Simanov, Kirill Ustyantsev, Katrien de Mulder, Margriet Grelling, Magda Grudniewska, Frank Beltman, Lisa Glazenburg, Turan Demircan, Julia Wunderer, Weihong Qi, Dita B. Vizoso, Philipp M. Weissert, Daniel Olivieri, Stijn Mouton, Victor Guryev, Aziz Aboobaker, Lukas Schärer, Peter Ladurner, Eugene Berezikov
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/51c6474ac76046948c59094214f7739d
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spelling oai:doaj.org-article:51c6474ac76046948c59094214f7739d2021-12-02T16:51:47ZEfficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano10.1038/s41467-017-02214-82041-1723https://doaj.org/article/51c6474ac76046948c59094214f7739d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02214-8https://doaj.org/toc/2041-1723Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequence.Jakub WudarskiDaniil SimanovKirill UstyantsevKatrien de MulderMargriet GrellingMagda GrudniewskaFrank BeltmanLisa GlazenburgTuran DemircanJulia WundererWeihong QiDita B. VizosoPhilipp M. WeissertDaniel OlivieriStijn MoutonVictor GuryevAziz AboobakerLukas SchärerPeter LadurnerEugene BerezikovNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jakub Wudarski
Daniil Simanov
Kirill Ustyantsev
Katrien de Mulder
Margriet Grelling
Magda Grudniewska
Frank Beltman
Lisa Glazenburg
Turan Demircan
Julia Wunderer
Weihong Qi
Dita B. Vizoso
Philipp M. Weissert
Daniel Olivieri
Stijn Mouton
Victor Guryev
Aziz Aboobaker
Lukas Schärer
Peter Ladurner
Eugene Berezikov
Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
description Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequence.
format article
author Jakub Wudarski
Daniil Simanov
Kirill Ustyantsev
Katrien de Mulder
Margriet Grelling
Magda Grudniewska
Frank Beltman
Lisa Glazenburg
Turan Demircan
Julia Wunderer
Weihong Qi
Dita B. Vizoso
Philipp M. Weissert
Daniel Olivieri
Stijn Mouton
Victor Guryev
Aziz Aboobaker
Lukas Schärer
Peter Ladurner
Eugene Berezikov
author_facet Jakub Wudarski
Daniil Simanov
Kirill Ustyantsev
Katrien de Mulder
Margriet Grelling
Magda Grudniewska
Frank Beltman
Lisa Glazenburg
Turan Demircan
Julia Wunderer
Weihong Qi
Dita B. Vizoso
Philipp M. Weissert
Daniel Olivieri
Stijn Mouton
Victor Guryev
Aziz Aboobaker
Lukas Schärer
Peter Ladurner
Eugene Berezikov
author_sort Jakub Wudarski
title Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
title_short Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
title_full Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
title_fullStr Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
title_full_unstemmed Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
title_sort efficient transgenesis and annotated genome sequence of the regenerative flatworm model macrostomum lignano
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/51c6474ac76046948c59094214f7739d
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