Optimality and sub-optimality in a bacterial growth law

Organisms improve their fitness by adjusting their gene expression to the environment, for example bacteria scale the expression of metabolic enzymes near linearly to their growth rate. Here, the authors show that such linear scaling often maximizes growth rate, but that linear scaling is suboptimal...

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Autores principales:	Benjamin D. Towbin, Yael Korem, Anat Bren, Shany Doron, Rotem Sorek, Uri Alon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/51d272c5dcc94ab993e4060b2a2052e1
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spelling	oai:doaj.org-article:51d272c5dcc94ab993e4060b2a2052e12021-12-02T14:42:03ZOptimality and sub-optimality in a bacterial growth law10.1038/ncomms141232041-1723https://doaj.org/article/51d272c5dcc94ab993e4060b2a2052e12017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14123https://doaj.org/toc/2041-1723Organisms improve their fitness by adjusting their gene expression to the environment, for example bacteria scale the expression of metabolic enzymes near linearly to their growth rate. Here, the authors show that such linear scaling often maximizes growth rate, but that linear scaling is suboptimal under some conditions.Benjamin D. TowbinYael KoremAnat BrenShany DoronRotem SorekUri AlonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin D. Towbin Yael Korem Anat Bren Shany Doron Rotem Sorek Uri Alon Optimality and sub-optimality in a bacterial growth law
description	Organisms improve their fitness by adjusting their gene expression to the environment, for example bacteria scale the expression of metabolic enzymes near linearly to their growth rate. Here, the authors show that such linear scaling often maximizes growth rate, but that linear scaling is suboptimal under some conditions.
format	article
author	Benjamin D. Towbin Yael Korem Anat Bren Shany Doron Rotem Sorek Uri Alon
author_facet	Benjamin D. Towbin Yael Korem Anat Bren Shany Doron Rotem Sorek Uri Alon
author_sort	Benjamin D. Towbin
title	Optimality and sub-optimality in a bacterial growth law
title_short	Optimality and sub-optimality in a bacterial growth law
title_full	Optimality and sub-optimality in a bacterial growth law
title_fullStr	Optimality and sub-optimality in a bacterial growth law
title_full_unstemmed	Optimality and sub-optimality in a bacterial growth law
title_sort	optimality and sub-optimality in a bacterial growth law
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/51d272c5dcc94ab993e4060b2a2052e1
work_keys_str_mv	AT benjamindtowbin optimalityandsuboptimalityinabacterialgrowthlaw AT yaelkorem optimalityandsuboptimalityinabacterialgrowthlaw AT anatbren optimalityandsuboptimalityinabacterialgrowthlaw AT shanydoron optimalityandsuboptimalityinabacterialgrowthlaw AT rotemsorek optimalityandsuboptimalityinabacterialgrowthlaw AT urialon optimalityandsuboptimalityinabacterialgrowthlaw
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Optimality and sub-optimality in a bacterial growth law

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