Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects

The protein Galectin-3 modulates host immunity and plays roles during infections. Here, Almeida et al. show that this protein contributes to host defence against infection with the fungal pathogen Cryptococcus neoformans by inhibiting fungal growth and inducing lysis of fungal extracellular vesicles...

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Autores principales:	Fausto Almeida, Julie M. Wolf, Thiago Aparecido da Silva, Carlos M. DeLeon-Rodriguez, Caroline Patini Rezende, André Moreira Pessoni, Fabrício Freitas Fernandes, Rafael Silva-Rocha, Roberto Martinez, Marcio L. Rodrigues, Maria Cristina Roque-Barreira, Arturo Casadevall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/51e4d237ab50421ba3097cb708688eb4
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spelling	oai:doaj.org-article:51e4d237ab50421ba3097cb708688eb42021-12-02T14:40:49ZGalectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects10.1038/s41467-017-02126-72041-1723https://doaj.org/article/51e4d237ab50421ba3097cb708688eb42017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02126-7https://doaj.org/toc/2041-1723The protein Galectin-3 modulates host immunity and plays roles during infections. Here, Almeida et al. show that this protein contributes to host defence against infection with the fungal pathogen Cryptococcus neoformans by inhibiting fungal growth and inducing lysis of fungal extracellular vesicles.Fausto AlmeidaJulie M. WolfThiago Aparecido da SilvaCarlos M. DeLeon-RodriguezCaroline Patini RezendeAndré Moreira PessoniFabrício Freitas FernandesRafael Silva-RochaRoberto MartinezMarcio L. RodriguesMaria Cristina Roque-BarreiraArturo CasadevallNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fausto Almeida Julie M. Wolf Thiago Aparecido da Silva Carlos M. DeLeon-Rodriguez Caroline Patini Rezende André Moreira Pessoni Fabrício Freitas Fernandes Rafael Silva-Rocha Roberto Martinez Marcio L. Rodrigues Maria Cristina Roque-Barreira Arturo Casadevall Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
description	The protein Galectin-3 modulates host immunity and plays roles during infections. Here, Almeida et al. show that this protein contributes to host defence against infection with the fungal pathogen Cryptococcus neoformans by inhibiting fungal growth and inducing lysis of fungal extracellular vesicles.
format	article
author	Fausto Almeida Julie M. Wolf Thiago Aparecido da Silva Carlos M. DeLeon-Rodriguez Caroline Patini Rezende André Moreira Pessoni Fabrício Freitas Fernandes Rafael Silva-Rocha Roberto Martinez Marcio L. Rodrigues Maria Cristina Roque-Barreira Arturo Casadevall
author_facet	Fausto Almeida Julie M. Wolf Thiago Aparecido da Silva Carlos M. DeLeon-Rodriguez Caroline Patini Rezende André Moreira Pessoni Fabrício Freitas Fernandes Rafael Silva-Rocha Roberto Martinez Marcio L. Rodrigues Maria Cristina Roque-Barreira Arturo Casadevall
author_sort	Fausto Almeida
title	Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
title_short	Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
title_full	Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
title_fullStr	Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
title_full_unstemmed	Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
title_sort	galectin-3 impacts cryptococcus neoformans infection through direct antifungal effects
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/51e4d237ab50421ba3097cb708688eb4
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Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects

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