Fractional response analysis reveals logarithmic cytokine responses in cellular populations

Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses of cellular populations.

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Detalles Bibliográficos
Autores principales: Karol Nienałtowski, Rachel E. Rigby, Jarosław Walczak, Karolina E. Zakrzewska, Edyta Głów, Jan Rehwinkel, Michał Komorowski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/51ea79c064944bc5ae1205ebb408cb88
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Sumario:Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses of cellular populations.