Fractional response analysis reveals logarithmic cytokine responses in cellular populations

Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses of cellular populations.

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Autores principales:	Karol Nienałtowski, Rachel E. Rigby, Jarosław Walczak, Karolina E. Zakrzewska, Edyta Głów, Jan Rehwinkel, Michał Komorowski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/51ea79c064944bc5ae1205ebb408cb88
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spelling	oai:doaj.org-article:51ea79c064944bc5ae1205ebb408cb882021-12-02T16:14:58ZFractional response analysis reveals logarithmic cytokine responses in cellular populations10.1038/s41467-021-24449-22041-1723https://doaj.org/article/51ea79c064944bc5ae1205ebb408cb882021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24449-2https://doaj.org/toc/2041-1723Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses of cellular populations.Karol NienałtowskiRachel E. RigbyJarosław WalczakKarolina E. ZakrzewskaEdyta GłówJan RehwinkelMichał KomorowskiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karol Nienałtowski Rachel E. Rigby Jarosław Walczak Karolina E. Zakrzewska Edyta Głów Jan Rehwinkel Michał Komorowski Fractional response analysis reveals logarithmic cytokine responses in cellular populations
description	Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses of cellular populations.
format	article
author	Karol Nienałtowski Rachel E. Rigby Jarosław Walczak Karolina E. Zakrzewska Edyta Głów Jan Rehwinkel Michał Komorowski
author_facet	Karol Nienałtowski Rachel E. Rigby Jarosław Walczak Karolina E. Zakrzewska Edyta Głów Jan Rehwinkel Michał Komorowski
author_sort	Karol Nienałtowski
title	Fractional response analysis reveals logarithmic cytokine responses in cellular populations
title_short	Fractional response analysis reveals logarithmic cytokine responses in cellular populations
title_full	Fractional response analysis reveals logarithmic cytokine responses in cellular populations
title_fullStr	Fractional response analysis reveals logarithmic cytokine responses in cellular populations
title_full_unstemmed	Fractional response analysis reveals logarithmic cytokine responses in cellular populations
title_sort	fractional response analysis reveals logarithmic cytokine responses in cellular populations
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/51ea79c064944bc5ae1205ebb408cb88
work_keys_str_mv	AT karolnienałtowski fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT rachelerigby fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT jarosławwalczak fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT karolinaezakrzewska fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT edytagłow fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT janrehwinkel fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations AT michałkomorowski fractionalresponseanalysisrevealslogarithmiccytokineresponsesincellularpopulations
_version_	1718384289652932608

Fractional response analysis reveals logarithmic cytokine responses in cellular populations

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