Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency ||Free Paper||

Richard F WalkerInternational Society for Applied Research in Aging (SARA)There is consensus among practitioners of age-management/longevity medicine that progressive failure of neuroendocrine function leads to hormone insufficiency, which underlies many of the maladaptive consequences of aging. Acc...

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Autor principal:	Richard F Walker
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/51edc7d0a62c4b5fb2c41f553a6d857b
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spelling	oai:doaj.org-article:51edc7d0a62c4b5fb2c41f553a6d857b2021-12-02T00:16:46ZEditorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|1178-1998https://doaj.org/article/51edc7d0a62c4b5fb2c41f553a6d857b2008-01-01T00:00:00Zhttps://www.dovepress.com/editorial-primary-locus-intervention-a-novel-approach-to-treating-age--peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Richard F WalkerInternational Society for Applied Research in Aging (SARA)There is consensus among practitioners of age-management/longevity medicine that progressive failure of neuroendocrine function leads to hormone insufficiency, which underlies many of the maladaptive consequences of aging. Accordingly, one of the most commonly employed clinical interventions in aging is balanced hormone replacement therapy (HRT). This approach is often quite effective since many of the structural and functional consequence of aging result at least in part from inadequate endogenous hormone supply and/or imbalance of multiple hormone actions upon the body. However, while HRT is effective in opposing many of the more obvious degenerative effects of aging on body composition and function it does little to treat the pathophysiological factors underlying neuroendocrine decline. In fact, HRT may actually accelerate senescence of neuroendocrine elements within the brain and pituitary gland.Richard F WalkerDove Medical PressarticleGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 2, Pp 495-497 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Geriatrics RC952-954.6
spellingShingle	Geriatrics RC952-954.6 Richard F Walker Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
description	Richard F WalkerInternational Society for Applied Research in Aging (SARA)There is consensus among practitioners of age-management/longevity medicine that progressive failure of neuroendocrine function leads to hormone insufficiency, which underlies many of the maladaptive consequences of aging. Accordingly, one of the most commonly employed clinical interventions in aging is balanced hormone replacement therapy (HRT). This approach is often quite effective since many of the structural and functional consequence of aging result at least in part from inadequate endogenous hormone supply and/or imbalance of multiple hormone actions upon the body. However, while HRT is effective in opposing many of the more obvious degenerative effects of aging on body composition and function it does little to treat the pathophysiological factors underlying neuroendocrine decline. In fact, HRT may actually accelerate senescence of neuroendocrine elements within the brain and pituitary gland.
format	article
author	Richard F Walker
author_facet	Richard F Walker
author_sort	Richard F Walker
title	Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
title_short	Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
title_full	Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
title_fullStr	Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
title_full_unstemmed	Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency \|\|Free Paper\|\|
title_sort	editorial: primary locus intervention: a novel approach to treating age-associated hormone insufficiency \|\|free paper\|\|
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/51edc7d0a62c4b5fb2c41f553a6d857b
work_keys_str_mv	AT richardfwalker editorialprimarylocusinterventionanovelapproachtotreatingageassociatedhormoneinsufficiencyfreepaper
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Editorial: Primary Locus Intervention: A novel approach to treating age-associated hormone insufficiency ||Free Paper||

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