Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards

Intertemporal choice involves the evaluation of future rewards and reflects behavioral impulsivity. After choosing a delayed reward in an intertemporal choice, a behavioral agent waits for, receives, and then consumes the reward. The current study focused on the consumption of the delayed reward and...

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Autores principales:	Ayaka Misonou, Koji Jimura
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	decision-making reward consumption delay discounting primary reward human Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/51ee5b7f82434aa28dc39ad7c6c5a464
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spelling	oai:doaj.org-article:51ee5b7f82434aa28dc39ad7c6c5a4642021-11-08T07:58:32ZPrefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards1662-515310.3389/fnbeh.2021.749252https://doaj.org/article/51ee5b7f82434aa28dc39ad7c6c5a4642021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnbeh.2021.749252/fullhttps://doaj.org/toc/1662-5153Intertemporal choice involves the evaluation of future rewards and reflects behavioral impulsivity. After choosing a delayed reward in an intertemporal choice, a behavioral agent waits for, receives, and then consumes the reward. The current study focused on the consumption of the delayed reward and examined the neural mechanisms of behavioral impulsivity. In humans consuming delayed real liquid rewards in an intertemporal choice, the ventral striatum (VS) showed differential activity between anterior (aVS) and posterior (pVS) regions depending on the degree of behavioral impulsivity. Additionally, impulsive individuals showed activity in the anterior prefrontal cortex (aPFC). An analysis of task-related effective connectivity based on psychophysiological interaction (PPI) revealed that PPI was robust from the aPFC to pVS, but not in the opposite direction. On the other hand, strong bidirectional PPIs were observed between the aVS and pVS, but PPIs from the pVS to aVS were enhanced in impulsive individuals. These results suggest that behavioral impulsivity is reflected in aPFC-VS mechanisms during the consumption of delayed real liquid rewards.Ayaka MisonouKoji JimuraFrontiers Media S.A.articledecision-makingreward consumptiondelay discountingprimary rewardhumanNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENFrontiers in Behavioral Neuroscience, Vol 15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	decision-making reward consumption delay discounting primary reward human Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	decision-making reward consumption delay discounting primary reward human Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Ayaka Misonou Koji Jimura Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
description	Intertemporal choice involves the evaluation of future rewards and reflects behavioral impulsivity. After choosing a delayed reward in an intertemporal choice, a behavioral agent waits for, receives, and then consumes the reward. The current study focused on the consumption of the delayed reward and examined the neural mechanisms of behavioral impulsivity. In humans consuming delayed real liquid rewards in an intertemporal choice, the ventral striatum (VS) showed differential activity between anterior (aVS) and posterior (pVS) regions depending on the degree of behavioral impulsivity. Additionally, impulsive individuals showed activity in the anterior prefrontal cortex (aPFC). An analysis of task-related effective connectivity based on psychophysiological interaction (PPI) revealed that PPI was robust from the aPFC to pVS, but not in the opposite direction. On the other hand, strong bidirectional PPIs were observed between the aVS and pVS, but PPIs from the pVS to aVS were enhanced in impulsive individuals. These results suggest that behavioral impulsivity is reflected in aPFC-VS mechanisms during the consumption of delayed real liquid rewards.
format	article
author	Ayaka Misonou Koji Jimura
author_facet	Ayaka Misonou Koji Jimura
author_sort	Ayaka Misonou
title	Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
title_short	Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
title_full	Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
title_fullStr	Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
title_full_unstemmed	Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards
title_sort	prefrontal-striatal mechanisms of behavioral impulsivity during consumption of delayed real liquid rewards
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/51ee5b7f82434aa28dc39ad7c6c5a464
work_keys_str_mv	AT ayakamisonou prefrontalstriatalmechanismsofbehavioralimpulsivityduringconsumptionofdelayedrealliquidrewards AT kojijimura prefrontalstriatalmechanismsofbehavioralimpulsivityduringconsumptionofdelayedrealliquidrewards
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Prefrontal-Striatal Mechanisms of Behavioral Impulsivity During Consumption of Delayed Real Liquid Rewards

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