Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans

Abstract This study assessed axial length and choroidal thickness changes following short-term peripheral myopic defocus in normal adult subjects. Twenty subjects underwent defocus sessions by viewing a full-field projected movie 4 m away for 4 h in the morning, while wearing spectacle lenses, corre...

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Autores principales:	Ryo Kubota, Nabin R. Joshi, Inna Samandarova, Maksud Oliva, Arkady Selenow, Amitava Gupta, Steven R. Ali
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5210104d942e4d228333afe7049cc94f
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spelling	oai:doaj.org-article:5210104d942e4d228333afe7049cc94f2021-11-28T12:20:32ZEffect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans10.1038/s41598-021-02043-22045-2322https://doaj.org/article/5210104d942e4d228333afe7049cc94f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02043-2https://doaj.org/toc/2045-2322Abstract This study assessed axial length and choroidal thickness changes following short-term peripheral myopic defocus in normal adult subjects. Twenty subjects underwent defocus sessions by viewing a full-field projected movie 4 m away for 4 h in the morning, while wearing spectacle lenses, corrected for distance vision in both eyes. The right eye, serving as the test eye, was peripherally defocused using a Fresnel lens overlay of + 3.50 D with a central clear aperture of 11.5 mm (correlating to a clear central visual field of approximately 23°), while the left eye served as the control (with no Fresnel lens overlay). A subset of 10 subjects from the same cohort also underwent additional defocus sessions with + 5.00 D of peripheral defocus. Axial length was measured and radial sub-foveal choroidal scans were obtained before and after the defocus sessions. The increase in axial length of the test eyes were significantly less than the control eyes under both peripheral defocus conditions (p < 0.05). The difference in mean change for choroidal thickness between test and control eyes was not significant for either dioptric condition. Our results demonstrated that short-term peripheral myopic defocus significantly inhibited axial elongation in adult humans, without significant changes in choroidal thickness.Ryo KubotaNabin R. JoshiInna SamandarovaMaksud OlivaArkady SelenowAmitava GuptaSteven R. AliNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ryo Kubota Nabin R. Joshi Inna Samandarova Maksud Oliva Arkady Selenow Amitava Gupta Steven R. Ali Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
description	Abstract This study assessed axial length and choroidal thickness changes following short-term peripheral myopic defocus in normal adult subjects. Twenty subjects underwent defocus sessions by viewing a full-field projected movie 4 m away for 4 h in the morning, while wearing spectacle lenses, corrected for distance vision in both eyes. The right eye, serving as the test eye, was peripherally defocused using a Fresnel lens overlay of + 3.50 D with a central clear aperture of 11.5 mm (correlating to a clear central visual field of approximately 23°), while the left eye served as the control (with no Fresnel lens overlay). A subset of 10 subjects from the same cohort also underwent additional defocus sessions with + 5.00 D of peripheral defocus. Axial length was measured and radial sub-foveal choroidal scans were obtained before and after the defocus sessions. The increase in axial length of the test eyes were significantly less than the control eyes under both peripheral defocus conditions (p < 0.05). The difference in mean change for choroidal thickness between test and control eyes was not significant for either dioptric condition. Our results demonstrated that short-term peripheral myopic defocus significantly inhibited axial elongation in adult humans, without significant changes in choroidal thickness.
format	article
author	Ryo Kubota Nabin R. Joshi Inna Samandarova Maksud Oliva Arkady Selenow Amitava Gupta Steven R. Ali
author_facet	Ryo Kubota Nabin R. Joshi Inna Samandarova Maksud Oliva Arkady Selenow Amitava Gupta Steven R. Ali
author_sort	Ryo Kubota
title	Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
title_short	Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
title_full	Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
title_fullStr	Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
title_full_unstemmed	Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans
title_sort	effect of short-term peripheral myopic defocus on ocular biometrics using fresnel “press-on” lenses in humans
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5210104d942e4d228333afe7049cc94f
work_keys_str_mv	AT ryokubota effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT nabinrjoshi effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT innasamandarova effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT maksudoliva effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT arkadyselenow effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT amitavagupta effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans AT stevenrali effectofshorttermperipheralmyopicdefocusonocularbiometricsusingfresnelpressonlensesinhumans
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Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans

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