Metastable hybridization-based DNA information storage to allow rapid and permanent erasure

The chemical stability of DNA makes complete erasure of DNA-encoded data difficult. Here the authors mix true and false messages, differentiated by whether a truth marker oligo is bound to it, and show that brief exposure to elevated temperatures randomizes the binding of truth markers preventing da...

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Autores principales: Jangwon Kim, Jin H. Bae, Michael Baym, David Yu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/521caa4ca79b45d38fd209aba923c447
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spelling oai:doaj.org-article:521caa4ca79b45d38fd209aba923c4472021-12-02T19:16:29ZMetastable hybridization-based DNA information storage to allow rapid and permanent erasure10.1038/s41467-020-18842-62041-1723https://doaj.org/article/521caa4ca79b45d38fd209aba923c4472020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18842-6https://doaj.org/toc/2041-1723The chemical stability of DNA makes complete erasure of DNA-encoded data difficult. Here the authors mix true and false messages, differentiated by whether a truth marker oligo is bound to it, and show that brief exposure to elevated temperatures randomizes the binding of truth markers preventing data recovery.Jangwon KimJin H. BaeMichael BaymDavid Yu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jangwon Kim
Jin H. Bae
Michael Baym
David Yu Zhang
Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
description The chemical stability of DNA makes complete erasure of DNA-encoded data difficult. Here the authors mix true and false messages, differentiated by whether a truth marker oligo is bound to it, and show that brief exposure to elevated temperatures randomizes the binding of truth markers preventing data recovery.
format article
author Jangwon Kim
Jin H. Bae
Michael Baym
David Yu Zhang
author_facet Jangwon Kim
Jin H. Bae
Michael Baym
David Yu Zhang
author_sort Jangwon Kim
title Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
title_short Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
title_full Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
title_fullStr Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
title_full_unstemmed Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
title_sort metastable hybridization-based dna information storage to allow rapid and permanent erasure
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/521caa4ca79b45d38fd209aba923c447
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AT jinhbae metastablehybridizationbaseddnainformationstoragetoallowrapidandpermanenterasure
AT michaelbaym metastablehybridizationbaseddnainformationstoragetoallowrapidandpermanenterasure
AT davidyuzhang metastablehybridizationbaseddnainformationstoragetoallowrapidandpermanenterasure
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