Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.

Guardado en:
Detalles Bibliográficos
Autores principales: Beben Benyamin, Ji He, Qiongyi Zhao, Jacob Gratten, Fleur Garton, Paul J. Leo, Zhijun Liu, Marie Mangelsdorf, Ammar Al-Chalabi, Lisa Anderson, Timothy J. Butler, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Matthew Devine, Janette Edson, Jennifer A. Fifita, Sarah Furlong, Ying-Ying Han, Jessica Harris, Anjali K. Henders, Rosalind L. Jeffree, Zi-Bing Jin, Zhongshan Li, Ting Li, Mengmeng Li, Yong Lin, Xiaolu Liu, Mhairi Marshall, Emily P. McCann, Bryan J. Mowry, Shyuan T. Ngo, Roger Pamphlett, Shu Ran, David C. Reutens, Dominic B. Rowe, Perminder Sachdev, Sonia Shah, Sharon Song, Li-Jun Tan, Lu Tang, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Robyn H. Wallace, Lawrie Wheeler, Kelly L. Williams, Jinyu Wu, Xin Wu, Jian Yang, Weihua Yue, Zong-Hong Zhang, Dai Zhang, Peter G. Noakes, Ian P. Blair, Robert D. Henderson, Pamela A. McCombe, Peter M. Visscher, Huji Xu, Perry F. Bartlett, Matthew A. Brown, Naomi R. Wray, Dongsheng Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/522153208176401ebf7630ef7ecef4a7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:522153208176401ebf7630ef7ecef4a7
record_format dspace
spelling oai:doaj.org-article:522153208176401ebf7630ef7ecef4a72021-12-02T14:41:20ZCross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis10.1038/s41467-017-00471-12041-1723https://doaj.org/article/522153208176401ebf7630ef7ecef4a72017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00471-1https://doaj.org/toc/2041-1723Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.Beben BenyaminJi HeQiongyi ZhaoJacob GrattenFleur GartonPaul J. LeoZhijun LiuMarie MangelsdorfAmmar Al-ChalabiLisa AndersonTimothy J. ButlerLu ChenXiang-Ding ChenKatie CreminHong-Weng DengMatthew DevineJanette EdsonJennifer A. FifitaSarah FurlongYing-Ying HanJessica HarrisAnjali K. HendersRosalind L. JeffreeZi-Bing JinZhongshan LiTing LiMengmeng LiYong LinXiaolu LiuMhairi MarshallEmily P. McCannBryan J. MowryShyuan T. NgoRoger PamphlettShu RanDavid C. ReutensDominic B. RowePerminder SachdevSonia ShahSharon SongLi-Jun TanLu TangLeonard H. van den BergWouter van RheenenJan H. VeldinkRobyn H. WallaceLawrie WheelerKelly L. WilliamsJinyu WuXin WuJian YangWeihua YueZong-Hong ZhangDai ZhangPeter G. NoakesIan P. BlairRobert D. HendersonPamela A. McCombePeter M. VisscherHuji XuPerry F. BartlettMatthew A. BrownNaomi R. WrayDongsheng FanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Beben Benyamin
Ji He
Qiongyi Zhao
Jacob Gratten
Fleur Garton
Paul J. Leo
Zhijun Liu
Marie Mangelsdorf
Ammar Al-Chalabi
Lisa Anderson
Timothy J. Butler
Lu Chen
Xiang-Ding Chen
Katie Cremin
Hong-Weng Deng
Matthew Devine
Janette Edson
Jennifer A. Fifita
Sarah Furlong
Ying-Ying Han
Jessica Harris
Anjali K. Henders
Rosalind L. Jeffree
Zi-Bing Jin
Zhongshan Li
Ting Li
Mengmeng Li
Yong Lin
Xiaolu Liu
Mhairi Marshall
Emily P. McCann
Bryan J. Mowry
Shyuan T. Ngo
Roger Pamphlett
Shu Ran
David C. Reutens
Dominic B. Rowe
Perminder Sachdev
Sonia Shah
Sharon Song
Li-Jun Tan
Lu Tang
Leonard H. van den Berg
Wouter van Rheenen
Jan H. Veldink
Robyn H. Wallace
Lawrie Wheeler
Kelly L. Williams
Jinyu Wu
Xin Wu
Jian Yang
Weihua Yue
Zong-Hong Zhang
Dai Zhang
Peter G. Noakes
Ian P. Blair
Robert D. Henderson
Pamela A. McCombe
Peter M. Visscher
Huji Xu
Perry F. Bartlett
Matthew A. Brown
Naomi R. Wray
Dongsheng Fan
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
description Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.
format article
author Beben Benyamin
Ji He
Qiongyi Zhao
Jacob Gratten
Fleur Garton
Paul J. Leo
Zhijun Liu
Marie Mangelsdorf
Ammar Al-Chalabi
Lisa Anderson
Timothy J. Butler
Lu Chen
Xiang-Ding Chen
Katie Cremin
Hong-Weng Deng
Matthew Devine
Janette Edson
Jennifer A. Fifita
Sarah Furlong
Ying-Ying Han
Jessica Harris
Anjali K. Henders
Rosalind L. Jeffree
Zi-Bing Jin
Zhongshan Li
Ting Li
Mengmeng Li
Yong Lin
Xiaolu Liu
Mhairi Marshall
Emily P. McCann
Bryan J. Mowry
Shyuan T. Ngo
Roger Pamphlett
Shu Ran
David C. Reutens
Dominic B. Rowe
Perminder Sachdev
Sonia Shah
Sharon Song
Li-Jun Tan
Lu Tang
Leonard H. van den Berg
Wouter van Rheenen
Jan H. Veldink
Robyn H. Wallace
Lawrie Wheeler
Kelly L. Williams
Jinyu Wu
Xin Wu
Jian Yang
Weihua Yue
Zong-Hong Zhang
Dai Zhang
Peter G. Noakes
Ian P. Blair
Robert D. Henderson
Pamela A. McCombe
Peter M. Visscher
Huji Xu
Perry F. Bartlett
Matthew A. Brown
Naomi R. Wray
Dongsheng Fan
author_facet Beben Benyamin
Ji He
Qiongyi Zhao
Jacob Gratten
Fleur Garton
Paul J. Leo
Zhijun Liu
Marie Mangelsdorf
Ammar Al-Chalabi
Lisa Anderson
Timothy J. Butler
Lu Chen
Xiang-Ding Chen
Katie Cremin
Hong-Weng Deng
Matthew Devine
Janette Edson
Jennifer A. Fifita
Sarah Furlong
Ying-Ying Han
Jessica Harris
Anjali K. Henders
Rosalind L. Jeffree
Zi-Bing Jin
Zhongshan Li
Ting Li
Mengmeng Li
Yong Lin
Xiaolu Liu
Mhairi Marshall
Emily P. McCann
Bryan J. Mowry
Shyuan T. Ngo
Roger Pamphlett
Shu Ran
David C. Reutens
Dominic B. Rowe
Perminder Sachdev
Sonia Shah
Sharon Song
Li-Jun Tan
Lu Tang
Leonard H. van den Berg
Wouter van Rheenen
Jan H. Veldink
Robyn H. Wallace
Lawrie Wheeler
Kelly L. Williams
Jinyu Wu
Xin Wu
Jian Yang
Weihua Yue
Zong-Hong Zhang
Dai Zhang
Peter G. Noakes
Ian P. Blair
Robert D. Henderson
Pamela A. McCombe
Peter M. Visscher
Huji Xu
Perry F. Bartlett
Matthew A. Brown
Naomi R. Wray
Dongsheng Fan
author_sort Beben Benyamin
title Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
title_short Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
title_full Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
title_fullStr Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
title_full_unstemmed Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
title_sort cross-ethnic meta-analysis identifies association of the gpx3-tnip1 locus with amyotrophic lateral sclerosis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/522153208176401ebf7630ef7ecef4a7
work_keys_str_mv AT bebenbenyamin crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jihe crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT qiongyizhao crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jacobgratten crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT fleurgarton crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT pauljleo crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT zhijunliu crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT mariemangelsdorf crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT ammaralchalabi crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT lisaanderson crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT timothyjbutler crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT luchen crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT xiangdingchen crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT katiecremin crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT hongwengdeng crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT matthewdevine crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT janetteedson crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jenniferafifita crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT sarahfurlong crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT yingyinghan crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jessicaharris crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT anjalikhenders crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT rosalindljeffree crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT zibingjin crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT zhongshanli crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT tingli crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT mengmengli crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT yonglin crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT xiaoluliu crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT mhairimarshall crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT emilypmccann crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT bryanjmowry crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT shyuantngo crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT rogerpamphlett crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT shuran crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT davidcreutens crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT dominicbrowe crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT permindersachdev crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT soniashah crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT sharonsong crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT lijuntan crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT lutang crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT leonardhvandenberg crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT woutervanrheenen crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT janhveldink crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT robynhwallace crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT lawriewheeler crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT kellylwilliams crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jinyuwu crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT xinwu crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT jianyang crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT weihuayue crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT zonghongzhang crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT daizhang crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT petergnoakes crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT ianpblair crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT robertdhenderson crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT pamelaamccombe crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT petermvisscher crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT hujixu crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT perryfbartlett crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT matthewabrown crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT naomirwray crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
AT dongshengfan crossethnicmetaanalysisidentifiesassociationofthegpx3tnip1locuswithamyotrophiclateralsclerosis
_version_ 1718389930584965120