Hepatitis C infection in Egypt: prevalence, impact and management strategies

Asmaa Gomaa,1 Naglaa Allam,1 Aisha Elsharkway,2 Mohamed El Kassas,3 Imam Waked1 1Hepatology Department, National Liver Institute, Shebeen EL Kom, 2Endemic Medicine Department, Faculty of Medicine, Cairo University, 3Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt Ab...

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Autores principales:	Gomaa A, Allam N, Elsharkawy A, El Kassas M, Waked I
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	hepatitis C in Egypt prevalence HCV burden treatment strategy Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/5222a4113af9465298d7e59e0304ca81
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spelling	oai:doaj.org-article:5222a4113af9465298d7e59e0304ca812021-12-02T07:54:32ZHepatitis C infection in Egypt: prevalence, impact and management strategies1179-1535https://doaj.org/article/5222a4113af9465298d7e59e0304ca812017-05-01T00:00:00Zhttps://www.dovepress.com/hepatitis-c-infection-in-egypt-prevalence-impact-and-management-strate-peer-reviewed-article-HMERhttps://doaj.org/toc/1179-1535Asmaa Gomaa,1 Naglaa Allam,1 Aisha Elsharkway,2 Mohamed El Kassas,3 Imam Waked1 1Hepatology Department, National Liver Institute, Shebeen EL Kom, 2Endemic Medicine Department, Faculty of Medicine, Cairo University, 3Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt Abstract: Hepatitis C virus (HCV) infection is a major public health burden in Egypt, where it bears the highest prevalence rate in the world. Estimates for prevalence are based upon data reported from the 2008 and 2015 Egypt Demographic Health Surveys. In this review, we demonstrate the prevalence results of both surveys and analyze the difference in the results. The overall HCV prevalence is estimated to be declining. However, the clinical impact of chronic HCV infection is expected to grow considerably. A mathematical model shows that by increasing the rate of treatment, the expected number of patients will decline significantly in 2030. The current and expected future burden of chronic HCV infection to the Egyptian economy, including direct and indirect costs due to disability and loss of lives, has been estimated and discussed in this review. The economic burden will continue to grow, but a model shows that the introduction of highly effective therapies will result in a significant reduction in the cumulative total economic burden of HCV by 2030. In recognition of the HCV tremendous health and economic burden, the Egyptian government established the National Committee for Control of Viral Hepatitis to implement an integrated nationwide strategy to provide patient care and ensure global treatment access. This review illustrates the epidemiological and disease burden aspects of HCV in Egypt in addition to introducing the national plan and program for managing HCV, which has been successful so far in treating a large number of patients, with the aim of achieving disease control and eventual elimination in Egypt. Keywords: hepatitis C in Egypt, prevalence, HCV burden, treatment strategyGomaa AAllam NElsharkawy AEl Kassas MWaked IDove Medical Pressarticlehepatitis C in EgyptprevalenceHCV burdentreatment strategyDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol Volume 9, Pp 17-25 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	hepatitis C in Egypt prevalence HCV burden treatment strategy Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	hepatitis C in Egypt prevalence HCV burden treatment strategy Diseases of the digestive system. Gastroenterology RC799-869 Gomaa A Allam N Elsharkawy A El Kassas M Waked I Hepatitis C infection in Egypt: prevalence, impact and management strategies
description	Asmaa Gomaa,1 Naglaa Allam,1 Aisha Elsharkway,2 Mohamed El Kassas,3 Imam Waked1 1Hepatology Department, National Liver Institute, Shebeen EL Kom, 2Endemic Medicine Department, Faculty of Medicine, Cairo University, 3Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt Abstract: Hepatitis C virus (HCV) infection is a major public health burden in Egypt, where it bears the highest prevalence rate in the world. Estimates for prevalence are based upon data reported from the 2008 and 2015 Egypt Demographic Health Surveys. In this review, we demonstrate the prevalence results of both surveys and analyze the difference in the results. The overall HCV prevalence is estimated to be declining. However, the clinical impact of chronic HCV infection is expected to grow considerably. A mathematical model shows that by increasing the rate of treatment, the expected number of patients will decline significantly in 2030. The current and expected future burden of chronic HCV infection to the Egyptian economy, including direct and indirect costs due to disability and loss of lives, has been estimated and discussed in this review. The economic burden will continue to grow, but a model shows that the introduction of highly effective therapies will result in a significant reduction in the cumulative total economic burden of HCV by 2030. In recognition of the HCV tremendous health and economic burden, the Egyptian government established the National Committee for Control of Viral Hepatitis to implement an integrated nationwide strategy to provide patient care and ensure global treatment access. This review illustrates the epidemiological and disease burden aspects of HCV in Egypt in addition to introducing the national plan and program for managing HCV, which has been successful so far in treating a large number of patients, with the aim of achieving disease control and eventual elimination in Egypt. Keywords: hepatitis C in Egypt, prevalence, HCV burden, treatment strategy
format	article
author	Gomaa A Allam N Elsharkawy A El Kassas M Waked I
author_facet	Gomaa A Allam N Elsharkawy A El Kassas M Waked I
author_sort	Gomaa A
title	Hepatitis C infection in Egypt: prevalence, impact and management strategies
title_short	Hepatitis C infection in Egypt: prevalence, impact and management strategies
title_full	Hepatitis C infection in Egypt: prevalence, impact and management strategies
title_fullStr	Hepatitis C infection in Egypt: prevalence, impact and management strategies
title_full_unstemmed	Hepatitis C infection in Egypt: prevalence, impact and management strategies
title_sort	hepatitis c infection in egypt: prevalence, impact and management strategies
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/5222a4113af9465298d7e59e0304ca81
work_keys_str_mv	AT gomaaa hepatitiscinfectioninegyptprevalenceimpactandmanagementstrategies AT allamn hepatitiscinfectioninegyptprevalenceimpactandmanagementstrategies AT elsharkawya hepatitiscinfectioninegyptprevalenceimpactandmanagementstrategies AT elkassasm hepatitiscinfectioninegyptprevalenceimpactandmanagementstrategies AT wakedi hepatitiscinfectioninegyptprevalenceimpactandmanagementstrategies
_version_	1718399102778081280

Hepatitis C infection in Egypt: prevalence, impact and management strategies

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