Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions

BACKGROUND AND OBJECTIVE: Gynecologic infections are the most common causes that women see a doctor. With regard to the high prevalence of vaginal candidiasis infections and side effects of chemical drugs and also reduction of their effectiveness against resistant strains, this study was designed to...

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Autores principales:	F Behmanesh, H Pasha, AA Sefidgar, AA Moghadamnia, A Ebrahimi Touri
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2010
Materias:	lavandula clotrimazole candida albicans microdilution method Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/522354ee52154e08bd7bf536a0663baa
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spelling	oai:doaj.org-article:522354ee52154e08bd7bf536a0663baa2021-11-10T09:00:30ZLavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions1561-41072251-7170https://doaj.org/article/522354ee52154e08bd7bf536a0663baa2010-08-01T00:00:00Zhttp://jbums.org/article-1-3628-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Gynecologic infections are the most common causes that women see a doctor. With regard to the high prevalence of vaginal candidiasis infections and side effects of chemical drugs and also reduction of their effectiveness against resistant strains, this study was designed to compare the effects of lavender and clotrimazole on the growth standard strains of Candida albicans in vitro conditions. METHODS: In this semi-experimental study, laboratory method of fungi cell counts by toma hemasimeter slide was used. In this method, after preparing dilution of 6 × 106 from standard Candida albicans S.C.a-PTCC-2657 in the liquid Saburo culture media and also add lavender essential oil, steam and clotrimazole in different dilution of (½, ¼, 1/8) and putting them into incubator for 48 hours (in 4 laboratory stages), fungal cell count was done with attention to inhibition of standard Candida multiplication. The tests were repeated twice for every drugs in different dilution of (½, ¼, 1/8). Samples characteristics and tests results were collected and compared.FINDINGS: The findings of this study showed that the number of fungi in test tubes which contained the lavender essential oil, lavender steam in comparison to control fungi had decreased dramatically (17× 106, 0.4×106 vs 188×106, respectively). Also, the count of fungal cell in the dilution ½ of drugs, the lavender steam was less than lavender essential oil and clotrimazole and in dilution of ¼ and 1/8, the lavender essential oil in comparison to lavender steam and clotrimazol had less count of fungi. The most antifungal efficacy of drugs was in the higher diluted. As among different dilutions (½, ¼ and 1/8), the lavender essential oil in dilution of ¼ and 1/8, and the lavender steam in dilution of 1/8 had been the more antifungal effect. In the all above dilutions, clotrimazole had the lowest antifungal efficacy and the most fungi cell counts.CONCLUSION: The results showed that the lavender essential oil and steam had more antifungal effect and efficacy against the standard Candida albicans in comparison to clotrimazole.F BehmaneshH Pasha,AA SefidgarAA MoghadamniaA Ebrahimi TouriBabol University of Medical Sciencesarticlelavandulaclotrimazolecandida albicansmicrodilution methodMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 3, Pp 26-31 (2010)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	lavandula clotrimazole candida albicans microdilution method Medicine R Medicine (General) R5-920
spellingShingle	lavandula clotrimazole candida albicans microdilution method Medicine R Medicine (General) R5-920 F Behmanesh H Pasha, AA Sefidgar AA Moghadamnia A Ebrahimi Touri Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
description	BACKGROUND AND OBJECTIVE: Gynecologic infections are the most common causes that women see a doctor. With regard to the high prevalence of vaginal candidiasis infections and side effects of chemical drugs and also reduction of their effectiveness against resistant strains, this study was designed to compare the effects of lavender and clotrimazole on the growth standard strains of Candida albicans in vitro conditions. METHODS: In this semi-experimental study, laboratory method of fungi cell counts by toma hemasimeter slide was used. In this method, after preparing dilution of 6 × 106 from standard Candida albicans S.C.a-PTCC-2657 in the liquid Saburo culture media and also add lavender essential oil, steam and clotrimazole in different dilution of (½, ¼, 1/8) and putting them into incubator for 48 hours (in 4 laboratory stages), fungal cell count was done with attention to inhibition of standard Candida multiplication. The tests were repeated twice for every drugs in different dilution of (½, ¼, 1/8). Samples characteristics and tests results were collected and compared.FINDINGS: The findings of this study showed that the number of fungi in test tubes which contained the lavender essential oil, lavender steam in comparison to control fungi had decreased dramatically (17× 106, 0.4×106 vs 188×106, respectively). Also, the count of fungal cell in the dilution ½ of drugs, the lavender steam was less than lavender essential oil and clotrimazole and in dilution of ¼ and 1/8, the lavender essential oil in comparison to lavender steam and clotrimazol had less count of fungi. The most antifungal efficacy of drugs was in the higher diluted. As among different dilutions (½, ¼ and 1/8), the lavender essential oil in dilution of ¼ and 1/8, and the lavender steam in dilution of 1/8 had been the more antifungal effect. In the all above dilutions, clotrimazole had the lowest antifungal efficacy and the most fungi cell counts.CONCLUSION: The results showed that the lavender essential oil and steam had more antifungal effect and efficacy against the standard Candida albicans in comparison to clotrimazole.
format	article
author	F Behmanesh H Pasha, AA Sefidgar AA Moghadamnia A Ebrahimi Touri
author_facet	F Behmanesh H Pasha, AA Sefidgar AA Moghadamnia A Ebrahimi Touri
author_sort	F Behmanesh
title	Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
title_short	Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
title_full	Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
title_fullStr	Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
title_full_unstemmed	Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions
title_sort	lavender and clotrimazol effect on the growth standard strains of c. albicans in vitro conditions
publisher	Babol University of Medical Sciences
publishDate	2010
url	https://doaj.org/article/522354ee52154e08bd7bf536a0663baa
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Lavender and Clotrimazol Effect on the Growth Standard Strains of C. Albicans in Vitro Conditions

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