Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions

ABSTRACT Gene expression has been considered a highly accurate process, and deviation from such fidelity has been shown previously to be detrimental for the cell. More recently, increasing evidence has supported the notion that the accuracy of gene expression is indeed flexibly variable. The levels...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Christopher R. Evans, Yongqiang Fan, Kalyn Weiss, Jiqiang Ling
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	mistranslation phenotypic heterogeneity protein synthesis stress response Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/522415f494684a5986f838a280f7b2eb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:522415f494684a5986f838a280f7b2eb
record_format	dspace
spelling	oai:doaj.org-article:522415f494684a5986f838a280f7b2eb2021-11-15T16:00:16ZErrors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions10.1128/mBio.01018-182150-7511https://doaj.org/article/522415f494684a5986f838a280f7b2eb2018-09-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01018-18https://doaj.org/toc/2150-7511ABSTRACT Gene expression has been considered a highly accurate process, and deviation from such fidelity has been shown previously to be detrimental for the cell. More recently, increasing evidence has supported the notion that the accuracy of gene expression is indeed flexibly variable. The levels of errors during gene expression differ from condition to condition and even from cell to cell within genetically identical populations grown under the same conditions. The different levels of errors resulting from inaccurate gene expression are now known to play key roles in regulating microbial stress responses and host interactions. This minireview summarizes the recent development in understanding the level, regulation, and physiological impact of errors during gene expression.Christopher R. EvansYongqiang FanKalyn WeissJiqiang LingAmerican Society for Microbiologyarticlemistranslationphenotypic heterogeneityprotein synthesisstress responseMicrobiologyQR1-502ENmBio, Vol 9, Iss 4 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	mistranslation phenotypic heterogeneity protein synthesis stress response Microbiology QR1-502
spellingShingle	mistranslation phenotypic heterogeneity protein synthesis stress response Microbiology QR1-502 Christopher R. Evans Yongqiang Fan Kalyn Weiss Jiqiang Ling Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
description	ABSTRACT Gene expression has been considered a highly accurate process, and deviation from such fidelity has been shown previously to be detrimental for the cell. More recently, increasing evidence has supported the notion that the accuracy of gene expression is indeed flexibly variable. The levels of errors during gene expression differ from condition to condition and even from cell to cell within genetically identical populations grown under the same conditions. The different levels of errors resulting from inaccurate gene expression are now known to play key roles in regulating microbial stress responses and host interactions. This minireview summarizes the recent development in understanding the level, regulation, and physiological impact of errors during gene expression.
format	article
author	Christopher R. Evans Yongqiang Fan Kalyn Weiss Jiqiang Ling
author_facet	Christopher R. Evans Yongqiang Fan Kalyn Weiss Jiqiang Ling
author_sort	Christopher R. Evans
title	Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
title_short	Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
title_full	Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
title_fullStr	Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
title_full_unstemmed	Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions
title_sort	errors during gene expression: single-cell heterogeneity, stress resistance, and microbe-host interactions
publisher	American Society for Microbiology
publishDate	2018
url	https://doaj.org/article/522415f494684a5986f838a280f7b2eb
work_keys_str_mv	AT christopherrevans errorsduringgeneexpressionsinglecellheterogeneitystressresistanceandmicrobehostinteractions AT yongqiangfan errorsduringgeneexpressionsinglecellheterogeneitystressresistanceandmicrobehostinteractions AT kalynweiss errorsduringgeneexpressionsinglecellheterogeneitystressresistanceandmicrobehostinteractions AT jiqiangling errorsduringgeneexpressionsinglecellheterogeneitystressresistanceandmicrobehostinteractions
_version_	1718426965344518144

Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbe-Host Interactions

Ejemplares similares