Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions

Current strategies for protein encapsulation in DNA vessels for controlled enzymatic catalysis or therapeutic delivery rely on formation of covalent complexes. Here, the authors design a system that mimics natural reversible non-covalent host–guest interactions between a DNA host and the protein Deg...

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Autores principales:	Andreas Sprengel, Pascal Lill, Pierre Stegemann, Kenny Bravo-Rodriguez, Elisa-C. Schöneweiß, Melisa Merdanovic, Daniel Gudnason, Mikayel Aznauryan, Lisa Gamrad, Stephan Barcikowski, Elsa Sanchez-Garcia, Victoria Birkedal, Christos Gatsogiannis, Michael Ehrmann, Barbara Saccà
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5226d94ebae64287be29caae8f6fe6be
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spelling	oai:doaj.org-article:5226d94ebae64287be29caae8f6fe6be2021-12-02T15:39:02ZTailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions10.1038/ncomms144722041-1723https://doaj.org/article/5226d94ebae64287be29caae8f6fe6be2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14472https://doaj.org/toc/2041-1723Current strategies for protein encapsulation in DNA vessels for controlled enzymatic catalysis or therapeutic delivery rely on formation of covalent complexes. Here, the authors design a system that mimics natural reversible non-covalent host–guest interactions between a DNA host and the protein DegP.Andreas SprengelPascal LillPierre StegemannKenny Bravo-RodriguezElisa-C. SchöneweißMelisa MerdanovicDaniel GudnasonMikayel AznauryanLisa GamradStephan BarcikowskiElsa Sanchez-GarciaVictoria BirkedalChristos GatsogiannisMichael EhrmannBarbara SaccàNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andreas Sprengel Pascal Lill Pierre Stegemann Kenny Bravo-Rodriguez Elisa-C. Schöneweiß Melisa Merdanovic Daniel Gudnason Mikayel Aznauryan Lisa Gamrad Stephan Barcikowski Elsa Sanchez-Garcia Victoria Birkedal Christos Gatsogiannis Michael Ehrmann Barbara Saccà Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
description	Current strategies for protein encapsulation in DNA vessels for controlled enzymatic catalysis or therapeutic delivery rely on formation of covalent complexes. Here, the authors design a system that mimics natural reversible non-covalent host–guest interactions between a DNA host and the protein DegP.
format	article
author	Andreas Sprengel Pascal Lill Pierre Stegemann Kenny Bravo-Rodriguez Elisa-C. Schöneweiß Melisa Merdanovic Daniel Gudnason Mikayel Aznauryan Lisa Gamrad Stephan Barcikowski Elsa Sanchez-Garcia Victoria Birkedal Christos Gatsogiannis Michael Ehrmann Barbara Saccà
author_facet	Andreas Sprengel Pascal Lill Pierre Stegemann Kenny Bravo-Rodriguez Elisa-C. Schöneweiß Melisa Merdanovic Daniel Gudnason Mikayel Aznauryan Lisa Gamrad Stephan Barcikowski Elsa Sanchez-Garcia Victoria Birkedal Christos Gatsogiannis Michael Ehrmann Barbara Saccà
author_sort	Andreas Sprengel
title	Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
title_short	Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
title_full	Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
title_fullStr	Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
title_full_unstemmed	Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions
title_sort	tailored protein encapsulation into a dna host using geometrically organized supramolecular interactions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5226d94ebae64287be29caae8f6fe6be
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Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions

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