Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs

Controlled patterning of functionality within hydrogels typically involves complex chemistry. Here, the authors report on a simple competitive binding strategy using avidin and biotin analogs in an injectable biomaterial for spatiotemporally controlled presentation of biochemical stimuli to cells.

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Autores principales:	Tom Kamperman, Michelle Koerselman, Cindy Kelder, Jan Hendriks, João F. Crispim, Xandra de Peuter, Pieter J. Dijkstra, Marcel Karperien, Jeroen Leijten
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/52362d610a0149c4b13c0cb447a41182
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spelling	oai:doaj.org-article:52362d610a0149c4b13c0cb447a411822021-12-02T14:40:18ZSpatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs10.1038/s41467-019-12390-42041-1723https://doaj.org/article/52362d610a0149c4b13c0cb447a411822019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12390-4https://doaj.org/toc/2041-1723Controlled patterning of functionality within hydrogels typically involves complex chemistry. Here, the authors report on a simple competitive binding strategy using avidin and biotin analogs in an injectable biomaterial for spatiotemporally controlled presentation of biochemical stimuli to cells.Tom KampermanMichelle KoerselmanCindy KelderJan HendriksJoão F. CrispimXandra de PeuterPieter J. DijkstraMarcel KarperienJeroen LeijtenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tom Kamperman Michelle Koerselman Cindy Kelder Jan Hendriks João F. Crispim Xandra de Peuter Pieter J. Dijkstra Marcel Karperien Jeroen Leijten Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
description	Controlled patterning of functionality within hydrogels typically involves complex chemistry. Here, the authors report on a simple competitive binding strategy using avidin and biotin analogs in an injectable biomaterial for spatiotemporally controlled presentation of biochemical stimuli to cells.
format	article
author	Tom Kamperman Michelle Koerselman Cindy Kelder Jan Hendriks João F. Crispim Xandra de Peuter Pieter J. Dijkstra Marcel Karperien Jeroen Leijten
author_facet	Tom Kamperman Michelle Koerselman Cindy Kelder Jan Hendriks João F. Crispim Xandra de Peuter Pieter J. Dijkstra Marcel Karperien Jeroen Leijten
author_sort	Tom Kamperman
title	Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
title_short	Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
title_full	Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
title_fullStr	Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
title_full_unstemmed	Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
title_sort	spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/52362d610a0149c4b13c0cb447a41182
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Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs

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