COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS

The aim of this work was to compare clinical features of severity and some basic indicators of immune state in the patients with chronic recurrent furunculosis (CRF), differing in levels of serum immunoglobulin E (IgE). In cases with increased IgE levels, the clinical course proved to be more severe...

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Autores principales:	T. A. Druzhinina, N. Yu. Alekseeva
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	furunculosis neutrophils immunoglobulin e Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/52393ce3448c4814b9f4a237c2dba84e
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spelling	oai:doaj.org-article:52393ce3448c4814b9f4a237c2dba84e2021-11-18T08:03:43ZCOMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS1563-06252313-741X10.15789/1563-0625-2014-3-295-300https://doaj.org/article/52393ce3448c4814b9f4a237c2dba84e2014-08-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/696https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe aim of this work was to compare clinical features of severity and some basic indicators of immune state in the patients with chronic recurrent furunculosis (CRF), differing in levels of serum immunoglobulin E (IgE). In cases with increased IgE levels, the clinical course proved to be more severe, as characterized by persistent recurrence of infection, with multiple lesions and weak inflammatory reaction, as compared with patients with normal IgE levels. Meanwhile, additional purulent skin lesions were less common among patients from this group. Comparative evaluation of basic anti-pyogenic defense effects allowed us to show a significant decrease of induced chemiluminescence of whole heparinized blood (p < 0.05) in patients with increased IgE levels, thus regarding it as a potential factor of more severe CRF clinical course in this cohort of patients.T. A. DruzhininaN. Yu. AlekseevaSPb RAACIarticlefurunculosisneutrophilsimmunoglobulin eImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 16, Iss 3, Pp 295-300 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	furunculosis neutrophils immunoglobulin e Immunologic diseases. Allergy RC581-607
spellingShingle	furunculosis neutrophils immunoglobulin e Immunologic diseases. Allergy RC581-607 T. A. Druzhinina N. Yu. Alekseeva COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
description	The aim of this work was to compare clinical features of severity and some basic indicators of immune state in the patients with chronic recurrent furunculosis (CRF), differing in levels of serum immunoglobulin E (IgE). In cases with increased IgE levels, the clinical course proved to be more severe, as characterized by persistent recurrence of infection, with multiple lesions and weak inflammatory reaction, as compared with patients with normal IgE levels. Meanwhile, additional purulent skin lesions were less common among patients from this group. Comparative evaluation of basic anti-pyogenic defense effects allowed us to show a significant decrease of induced chemiluminescence of whole heparinized blood (p < 0.05) in patients with increased IgE levels, thus regarding it as a potential factor of more severe CRF clinical course in this cohort of patients.
format	article
author	T. A. Druzhinina N. Yu. Alekseeva
author_facet	T. A. Druzhinina N. Yu. Alekseeva
author_sort	T. A. Druzhinina
title	COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
title_short	COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
title_full	COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
title_fullStr	COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
title_full_unstemmed	COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS
title_sort	comparative evaluation of chronic recurrent furunculosis and phagocytic component of immunity among patients differing in ige levels
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/52393ce3448c4814b9f4a237c2dba84e
work_keys_str_mv	AT tadruzhinina comparativeevaluationofchronicrecurrentfurunculosisandphagocyticcomponentofimmunityamongpatientsdifferinginigelevels AT nyualekseeva comparativeevaluationofchronicrecurrentfurunculosisandphagocyticcomponentofimmunityamongpatientsdifferinginigelevels
_version_	1718422416306208768

COMPARATIVE EVALUATION OF CHRONIC RECURRENT FURUNCULOSIS AND PHAGOCYTIC COMPONENT OF IMMUNITY AMONG PATIENTS DIFFERING IN IgE LEVELS

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