Respiratory chain components are required for peptidoglycan recognition protein-induced thiol depletion and killing in Bacillus subtilis and Escherichia coli

Abstract Mammalian peptidoglycan recognition proteins (PGRPs or PGLYRPs) kill bacteria through induction of synergistic oxidative, thiol, and metal stress. Tn-seq screening of Bacillus subtilis transposon insertion library revealed that mutants in the shikimate pathway of chorismate synthesis had hi...

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Bibliographic Details
Main Authors: Chun-Kai Yang, Des R. Kashyap, Dominik A. Kowalczyk, David Z. Rudner, Xindan Wang, Dipika Gupta, Roman Dziarski
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/5242925f79604c4da0d4aa89b70fd364
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