Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents

ABSTRACT Our firm conducted a risk/benefit assessment of “gain-of-function” research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Sel...

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Autores principales:	Ryan Ritterson, Rocco Casagrande
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2017
Materias:	biosafety conduct of research gain of function science policy Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/524573665b524fe09286c67c96536dd2
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spelling	oai:doaj.org-article:524573665b524fe09286c67c96536dd22021-11-15T15:21:45ZBasic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents10.1128/mSphere.00010-172379-5042https://doaj.org/article/524573665b524fe09286c67c96536dd22017-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00010-17https://doaj.org/toc/2379-5042ABSTRACT Our firm conducted a risk/benefit assessment of “gain-of-function” research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza, MERS, and SARS Viruses, 2014). Due to significant missing but theoretically acquirable data, our biosafety assessment faced limitations, and we were forced to provide a relative, instead of absolute, measure of risk (Gryphon Scientific, LLC, Risk and Benefit Analysis of Gain of Function Research, 2016). Here, we argue that many of these types of missing data represent large and stunning gaps in our knowledge of biosafety and argue that these missing data, once acquired via primary research efforts, would improve biosafety risk assessments and could be incorporated into biosafety practices to reduce risk of accidents. Governments invest billions in biological research; at least a small fraction of this support is warranted to prevent biological accidents.Ryan RittersonRocco CasagrandeAmerican Society for Microbiologyarticlebiosafetyconduct of researchgain of functionscience policyMicrobiologyQR1-502ENmSphere, Vol 2, Iss 2 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	biosafety conduct of research gain of function science policy Microbiology QR1-502
spellingShingle	biosafety conduct of research gain of function science policy Microbiology QR1-502 Ryan Ritterson Rocco Casagrande Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
description	ABSTRACT Our firm conducted a risk/benefit assessment of “gain-of-function” research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza, MERS, and SARS Viruses, 2014). Due to significant missing but theoretically acquirable data, our biosafety assessment faced limitations, and we were forced to provide a relative, instead of absolute, measure of risk (Gryphon Scientific, LLC, Risk and Benefit Analysis of Gain of Function Research, 2016). Here, we argue that many of these types of missing data represent large and stunning gaps in our knowledge of biosafety and argue that these missing data, once acquired via primary research efforts, would improve biosafety risk assessments and could be incorporated into biosafety practices to reduce risk of accidents. Governments invest billions in biological research; at least a small fraction of this support is warranted to prevent biological accidents.
format	article
author	Ryan Ritterson Rocco Casagrande
author_facet	Ryan Ritterson Rocco Casagrande
author_sort	Ryan Ritterson
title	Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
title_short	Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
title_full	Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
title_fullStr	Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
title_full_unstemmed	Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents
title_sort	basic scholarship in biosafety is critically needed to reduce risk of laboratory accidents
publisher	American Society for Microbiology
publishDate	2017
url	https://doaj.org/article/524573665b524fe09286c67c96536dd2
work_keys_str_mv	AT ryanritterson basicscholarshipinbiosafetyiscriticallyneededtoreduceriskoflaboratoryaccidents AT roccocasagrande basicscholarshipinbiosafetyiscriticallyneededtoreduceriskoflaboratoryaccidents
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Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents

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