Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy
Abstract Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear. Transforming Growth Factor- β1 (TGF-β), a key player in the pathogenesis of DN, regulates expressi...
Guardado en:
Autores principales: | Supriya Deshpande, Maryam Abdollahi, Mei Wang, Linda Lanting, Mitsuo Kato, Rama Natarajan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5255ac3e313a425f815d571d439fd77b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy
por: Mitsuo Kato, et al.
Publicado: (2016) -
Diabetic condition induces hypertrophy and vacuolization in glomerular parietal epithelial cells
por: Takahisa Kawaguchi, et al.
Publicado: (2021) -
Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney
por: Abhijit S. Naik, et al.
Publicado: (2021) -
Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy
por: Chen-Yun Chen, et al.
Publicado: (2021) -
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
por: Andrea Raso, et al.
Publicado: (2021)