Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing
Precise chromosome segregation during mitosis requires coordination of stable chromosome bi-orientation with anaphase onset, however the underlying mechanism is not clear. Here the authors show that inner centromere localization of the chromosomal passenger complex maintains centromeric cohesion on...
Guardado en:
Autores principales: | Rutger C. C. Hengeveld, Martijn J. M. Vromans, Mathijs Vleugel, Michael A. Hadders, Susanne M. A. Lens |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/52565a2b172f4948a7daae61f2125042 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
por: Grégory Eot-Houllier, et al.
Publicado: (2018) -
Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state.
por: Lisa Prendergast, et al.
Publicado: (2011) -
The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA
por: V. Barra, et al.
Publicado: (2018) -
Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
por: Dongqing Pan, et al.
Publicado: (2019) -
A Dynamical Model for Activating and Silencing the Mitotic Checkpoint
por: Richard Henze, et al.
Publicado: (2017)