Long-lasting severe immune dysfunction in Ebola virus disease survivors
Patients who have recovered from Ebola virus can have ongoing health problems. Here, the authors show that 35 Guinean survivors of the last West African Ebola epidemic have a chronic disease with high inflammatory cytokine expression and other markers of immune activation as well as evidence of inte...
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Nature Portfolio
2020
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oai:doaj.org-article:525bc83b567f4212a1ba8e49aa1000612021-12-02T17:57:17ZLong-lasting severe immune dysfunction in Ebola virus disease survivors10.1038/s41467-020-17489-72041-1723https://doaj.org/article/525bc83b567f4212a1ba8e49aa1000612020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17489-7https://doaj.org/toc/2041-1723Patients who have recovered from Ebola virus can have ongoing health problems. Here, the authors show that 35 Guinean survivors of the last West African Ebola epidemic have a chronic disease with high inflammatory cytokine expression and other markers of immune activation as well as evidence of intestinal tissue damage nearly two years after their release from hospital.Aurélie WiedemannEmile FoucatHakim HociniCécile LefebvreBoris P. HejblumMélany DurandMiriam KrügerAlpha Kabinet KeitaAhidjo AyoubaStéphane MélyJosé-Carlos FernandezAbdoulaye TouréSlim FouratiClaire Lévy-MarchalHervé RaoulEric DelaporteLamine KoivoguiRodolphe ThiébautChristine LacabaratzYves LévyPostEboGui Study GroupNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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DOAJ |
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DOAJ |
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EN |
| topic |
Science Q |
| spellingShingle |
Science Q Aurélie Wiedemann Emile Foucat Hakim Hocini Cécile Lefebvre Boris P. Hejblum Mélany Durand Miriam Krüger Alpha Kabinet Keita Ahidjo Ayouba Stéphane Mély José-Carlos Fernandez Abdoulaye Touré Slim Fourati Claire Lévy-Marchal Hervé Raoul Eric Delaporte Lamine Koivogui Rodolphe Thiébaut Christine Lacabaratz Yves Lévy PostEboGui Study Group Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| description |
Patients who have recovered from Ebola virus can have ongoing health problems. Here, the authors show that 35 Guinean survivors of the last West African Ebola epidemic have a chronic disease with high inflammatory cytokine expression and other markers of immune activation as well as evidence of intestinal tissue damage nearly two years after their release from hospital. |
| format |
article |
| author |
Aurélie Wiedemann Emile Foucat Hakim Hocini Cécile Lefebvre Boris P. Hejblum Mélany Durand Miriam Krüger Alpha Kabinet Keita Ahidjo Ayouba Stéphane Mély José-Carlos Fernandez Abdoulaye Touré Slim Fourati Claire Lévy-Marchal Hervé Raoul Eric Delaporte Lamine Koivogui Rodolphe Thiébaut Christine Lacabaratz Yves Lévy PostEboGui Study Group |
| author_facet |
Aurélie Wiedemann Emile Foucat Hakim Hocini Cécile Lefebvre Boris P. Hejblum Mélany Durand Miriam Krüger Alpha Kabinet Keita Ahidjo Ayouba Stéphane Mély José-Carlos Fernandez Abdoulaye Touré Slim Fourati Claire Lévy-Marchal Hervé Raoul Eric Delaporte Lamine Koivogui Rodolphe Thiébaut Christine Lacabaratz Yves Lévy PostEboGui Study Group |
| author_sort |
Aurélie Wiedemann |
| title |
Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| title_short |
Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| title_full |
Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| title_fullStr |
Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| title_full_unstemmed |
Long-lasting severe immune dysfunction in Ebola virus disease survivors |
| title_sort |
long-lasting severe immune dysfunction in ebola virus disease survivors |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/525bc83b567f4212a1ba8e49aa100061 |
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