Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain

Semaphorins and their receptors are involved in neurodevelopment, but their functions in the adult nervous system are not fully understood. This study finds that semaphorin 4C and its receptor Plexin B are expressed in sensory neurons and are pronociceptive in a mouse model of inflammatory pain.

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Autores principales:	Eszter Paldy, Manuela Simonetti, Thomas Worzfeld, Kiran Kumar Bali, Lucas Vicuña, Stefan Offermanns, Rohini Kuner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/527b909c401a4c5ebcc7de37bff5164a
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spelling	oai:doaj.org-article:527b909c401a4c5ebcc7de37bff5164a2021-12-02T10:48:28ZSemaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain10.1038/s41467-017-00341-w2041-1723https://doaj.org/article/527b909c401a4c5ebcc7de37bff5164a2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00341-whttps://doaj.org/toc/2041-1723Semaphorins and their receptors are involved in neurodevelopment, but their functions in the adult nervous system are not fully understood. This study finds that semaphorin 4C and its receptor Plexin B are expressed in sensory neurons and are pronociceptive in a mouse model of inflammatory pain.Eszter PaldyManuela SimonettiThomas WorzfeldKiran Kumar BaliLucas VicuñaStefan OffermannsRohini KunerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eszter Paldy Manuela Simonetti Thomas Worzfeld Kiran Kumar Bali Lucas Vicuña Stefan Offermanns Rohini Kuner Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
description	Semaphorins and their receptors are involved in neurodevelopment, but their functions in the adult nervous system are not fully understood. This study finds that semaphorin 4C and its receptor Plexin B are expressed in sensory neurons and are pronociceptive in a mouse model of inflammatory pain.
format	article
author	Eszter Paldy Manuela Simonetti Thomas Worzfeld Kiran Kumar Bali Lucas Vicuña Stefan Offermanns Rohini Kuner
author_facet	Eszter Paldy Manuela Simonetti Thomas Worzfeld Kiran Kumar Bali Lucas Vicuña Stefan Offermanns Rohini Kuner
author_sort	Eszter Paldy
title	Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
title_short	Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
title_full	Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
title_fullStr	Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
title_full_unstemmed	Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
title_sort	semaphorin 4c plexin-b2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/527b909c401a4c5ebcc7de37bff5164a
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Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain

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