Benzodiazepine and Z-drug consumption in a national social security organization in Argentina: rational or excessive use?

Benzodiazepines and “Z-drugs” (BZD/Z) are overprescribed in many countries. This study evaluates their consumption in a social security sector health insurance provider with national coverage in Argentina. With a descriptive and observational approach, outpatient dispensations of BZD/Zs were analyze...

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Autores principales: Gustavo Marin, Julieta Del Mauro, Lupe Marin, Martin A. Urtasun, Gina Marin, Daniel Nucher, Carlos Dacher, Dario Diaz Perez, Martín Cañás
Formato: article
Lenguaje:EN
ES
Publicado: Instituto de Salud Colectiva, Universidad Nacional de Lanús 2021
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Acceso en línea:https://doaj.org/article/52891a177f0b40498042828086643b0f
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Sumario:Benzodiazepines and “Z-drugs” (BZD/Z) are overprescribed in many countries. This study evaluates their consumption in a social security sector health insurance provider with national coverage in Argentina. With a descriptive and observational approach, outpatient dispensations of BZD/Zs were analyzed for people over 18 years old from April 2020 to March 2021, disaggregated by sex, age, active ingredient, and half-life. An annual prevalence of use of 11.6% was found among the 431,445 adult affiliates, with higher rates in women and in those over age 60. Overall consumption of BZD/Zs was 77.6 defined daily doses (DDD) per 1000 enrollee-days. The average user received 5.1 annual dispensations and the equivalent of 1.4 DDD for each day of the year. BZD/Zs with long half-life were the most used. We found high levels of BZD/Z consumption and for longer periods than recommended. It is necessary to improve the quality of consumption and reduce the negative impact of inappropriate use of these drugs among treated individuals.