Chronic relapsing inflammatory optic neuropathy: description of two clinical cases

Aim. To study the features of the clinical course, diagnosis and treatment of chronic relapsing inflammatory optic neuropathy based on clinical cases. Materials and Methods. Clinical cases of chronic relapsing inflammatory optic neuropathy in two men are presented. The patients underwent neurolog...

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Autores principales: T.I. Nehrych, M.B. Kopchak, S.Ya. Kyryliuk
Formato: article
Lenguaje:EN
UK
Publicado: Danylo Halytsky Lviv National Medical University 2020
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Acceso en línea:https://doaj.org/article/529800c8bdf0459096a9eeb3e161ca9f
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spelling oai:doaj.org-article:529800c8bdf0459096a9eeb3e161ca9f2021-11-10T19:49:51ZChronic relapsing inflammatory optic neuropathy: description of two clinical cases1029-42442415-330310.25040/aml2020.04.116https://doaj.org/article/529800c8bdf0459096a9eeb3e161ca9f2020-12-01T00:00:00Zhttps://amljournal.com/index.php/journal/article/view/17https://doaj.org/toc/1029-4244https://doaj.org/toc/2415-3303Aim. To study the features of the clinical course, diagnosis and treatment of chronic relapsing inflammatory optic neuropathy based on clinical cases. Materials and Methods. Clinical cases of chronic relapsing inflammatory optic neuropathy in two men are presented. The patients underwent neurological and ophthalmological examination, laboratory blood tests, testing of cerebrospinal fluid, magnetic resonance imaging of the brain and spinal cord, perimetry, ophtalmoscopy, optical coherence tomography, ultrasound examination of internal organs and of the branches of the aortic arch, and chest radiography. Results and Discussion. Two cases of chronic relapsing inflammatory optic neuropathy were described in two men aged 44 and 22 years. Episodes of recurrent optic neuritis, both unilateral and bilateral, were observed in patients; their vision improved after corticosteroid therapy. No etiological factors or comorbidities capable of causing the condition were identified. The older patient had 8 attacks of recurrent optic neuritis, with complete recovery of vision after therapy in seven cases, and partial recovery after the last relapse . The 22-year-old patient endured 5 episodes without complete recovery of vision after treatment. Based on the diagnostic criteria of chronic recurrent inflammatory optic neuropathy, this diagnosis was suspected in the patients. Conclusions. Chronic relapsing inflammatory optic neuropathy is a rare pathology whose clinical manifestations must meet diagnostic criteria. Patients with recurrent optic neuritis are to be well examined, in order to make a correct diagnosis and prescribe adequate therapy. Clinical manifestations of chronic relapsing inflammatory optic neuropathy tend to regress and stabilize against a background of immunosuppressive therapy.T.I. NehrychM.B. KopchakS.Ya. KyryliukDanylo Halytsky Lviv National Medical Universityarticlechronic relapsing inflammatory optic neuropathy, clinical casesMedicine (General)R5-920ENUKActa Medica Leopoliensia, Vol 26, Iss 4, Pp 116-121 (2020)
institution DOAJ
collection DOAJ
language EN
UK
topic chronic relapsing inflammatory optic neuropathy, clinical cases
Medicine (General)
R5-920
spellingShingle chronic relapsing inflammatory optic neuropathy, clinical cases
Medicine (General)
R5-920
T.I. Nehrych
M.B. Kopchak
S.Ya. Kyryliuk
Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
description Aim. To study the features of the clinical course, diagnosis and treatment of chronic relapsing inflammatory optic neuropathy based on clinical cases. Materials and Methods. Clinical cases of chronic relapsing inflammatory optic neuropathy in two men are presented. The patients underwent neurological and ophthalmological examination, laboratory blood tests, testing of cerebrospinal fluid, magnetic resonance imaging of the brain and spinal cord, perimetry, ophtalmoscopy, optical coherence tomography, ultrasound examination of internal organs and of the branches of the aortic arch, and chest radiography. Results and Discussion. Two cases of chronic relapsing inflammatory optic neuropathy were described in two men aged 44 and 22 years. Episodes of recurrent optic neuritis, both unilateral and bilateral, were observed in patients; their vision improved after corticosteroid therapy. No etiological factors or comorbidities capable of causing the condition were identified. The older patient had 8 attacks of recurrent optic neuritis, with complete recovery of vision after therapy in seven cases, and partial recovery after the last relapse . The 22-year-old patient endured 5 episodes without complete recovery of vision after treatment. Based on the diagnostic criteria of chronic recurrent inflammatory optic neuropathy, this diagnosis was suspected in the patients. Conclusions. Chronic relapsing inflammatory optic neuropathy is a rare pathology whose clinical manifestations must meet diagnostic criteria. Patients with recurrent optic neuritis are to be well examined, in order to make a correct diagnosis and prescribe adequate therapy. Clinical manifestations of chronic relapsing inflammatory optic neuropathy tend to regress and stabilize against a background of immunosuppressive therapy.
format article
author T.I. Nehrych
M.B. Kopchak
S.Ya. Kyryliuk
author_facet T.I. Nehrych
M.B. Kopchak
S.Ya. Kyryliuk
author_sort T.I. Nehrych
title Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
title_short Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
title_full Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
title_fullStr Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
title_full_unstemmed Chronic relapsing inflammatory optic neuropathy: description of two clinical cases
title_sort chronic relapsing inflammatory optic neuropathy: description of two clinical cases
publisher Danylo Halytsky Lviv National Medical University
publishDate 2020
url https://doaj.org/article/529800c8bdf0459096a9eeb3e161ca9f
work_keys_str_mv AT tinehrych chronicrelapsinginflammatoryopticneuropathydescriptionoftwoclinicalcases
AT mbkopchak chronicrelapsinginflammatoryopticneuropathydescriptionoftwoclinicalcases
AT syakyryliuk chronicrelapsinginflammatoryopticneuropathydescriptionoftwoclinicalcases
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