In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair

XPD is part of the TFIIH complex which plays major roles in transcription initiation and nucleotide excision repair (NER). Here the authors present a high-resolution crystal structure of the XPD-MAT1 interface and dissect the role of this interface in transcription and NER.

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Autores principales:	Stefan Peissert, Florian Sauer, Daniel B. Grabarczyk, Cathy Braun, Gudrun Sander, Arnaud Poterszman, Jean-Marc Egly, Jochen Kuper, Caroline Kisker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/52a2dac0f1f34c4a966c28ea3af6e495
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spelling	oai:doaj.org-article:52a2dac0f1f34c4a966c28ea3af6e4952021-12-02T14:40:54ZIn TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair10.1038/s41467-020-15241-92041-1723https://doaj.org/article/52a2dac0f1f34c4a966c28ea3af6e4952020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15241-9https://doaj.org/toc/2041-1723XPD is part of the TFIIH complex which plays major roles in transcription initiation and nucleotide excision repair (NER). Here the authors present a high-resolution crystal structure of the XPD-MAT1 interface and dissect the role of this interface in transcription and NER.Stefan PeissertFlorian SauerDaniel B. GrabarczykCathy BraunGudrun SanderArnaud PoterszmanJean-Marc EglyJochen KuperCaroline KiskerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stefan Peissert Florian Sauer Daniel B. Grabarczyk Cathy Braun Gudrun Sander Arnaud Poterszman Jean-Marc Egly Jochen Kuper Caroline Kisker In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
description	XPD is part of the TFIIH complex which plays major roles in transcription initiation and nucleotide excision repair (NER). Here the authors present a high-resolution crystal structure of the XPD-MAT1 interface and dissect the role of this interface in transcription and NER.
format	article
author	Stefan Peissert Florian Sauer Daniel B. Grabarczyk Cathy Braun Gudrun Sander Arnaud Poterszman Jean-Marc Egly Jochen Kuper Caroline Kisker
author_facet	Stefan Peissert Florian Sauer Daniel B. Grabarczyk Cathy Braun Gudrun Sander Arnaud Poterszman Jean-Marc Egly Jochen Kuper Caroline Kisker
author_sort	Stefan Peissert
title	In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
title_short	In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
title_full	In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
title_fullStr	In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
title_full_unstemmed	In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
title_sort	in tfiih the arch domain of xpd is mechanistically essential for transcription and dna repair
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/52a2dac0f1f34c4a966c28ea3af6e495
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In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair

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