Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming

The interaction between RIM and the C2A domain of Munc13 is known to be required for synaptic vesicle priming. Here the authors show new implications of the C2A domain of Munc13, through its dynamic interaction with RIM, in orchestrating a wide range of modulatory operations that shape vesicle docki...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Marcial Camacho, Jayeeta Basu, Thorsten Trimbuch, Shuwen Chang, Cristina Pulido-Lozano, Shwu-Shin Chang, Irina Duluvova, Masin Abo-Rady, Josep Rizo, Christian Rosenmund
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/52a5936a1e17420b818768e85afd9042
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:52a5936a1e17420b818768e85afd9042
record_format	dspace
spelling	oai:doaj.org-article:52a5936a1e17420b818768e85afd90422021-12-02T17:06:17ZHeterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming10.1038/ncomms152932041-1723https://doaj.org/article/52a5936a1e17420b818768e85afd90422017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15293https://doaj.org/toc/2041-1723The interaction between RIM and the C2A domain of Munc13 is known to be required for synaptic vesicle priming. Here the authors show new implications of the C2A domain of Munc13, through its dynamic interaction with RIM, in orchestrating a wide range of modulatory operations that shape vesicle docking, priming and neurotransmitter release.Marcial CamachoJayeeta BasuThorsten TrimbuchShuwen ChangCristina Pulido-LozanoShwu-Shin ChangIrina DuluvovaMasin Abo-RadyJosep RizoChristian RosenmundNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marcial Camacho Jayeeta Basu Thorsten Trimbuch Shuwen Chang Cristina Pulido-Lozano Shwu-Shin Chang Irina Duluvova Masin Abo-Rady Josep Rizo Christian Rosenmund Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
description	The interaction between RIM and the C2A domain of Munc13 is known to be required for synaptic vesicle priming. Here the authors show new implications of the C2A domain of Munc13, through its dynamic interaction with RIM, in orchestrating a wide range of modulatory operations that shape vesicle docking, priming and neurotransmitter release.
format	article
author	Marcial Camacho Jayeeta Basu Thorsten Trimbuch Shuwen Chang Cristina Pulido-Lozano Shwu-Shin Chang Irina Duluvova Masin Abo-Rady Josep Rizo Christian Rosenmund
author_facet	Marcial Camacho Jayeeta Basu Thorsten Trimbuch Shuwen Chang Cristina Pulido-Lozano Shwu-Shin Chang Irina Duluvova Masin Abo-Rady Josep Rizo Christian Rosenmund
author_sort	Marcial Camacho
title	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
title_short	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
title_full	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
title_fullStr	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
title_full_unstemmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming
title_sort	heterodimerization of munc13 c2a domain with rim regulates synaptic vesicle docking and priming
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/52a5936a1e17420b818768e85afd9042
work_keys_str_mv	AT marcialcamacho heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT jayeetabasu heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT thorstentrimbuch heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT shuwenchang heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT cristinapulidolozano heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT shwushinchang heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT irinaduluvova heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT masinaborady heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT joseprizo heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming AT christianrosenmund heterodimerizationofmunc13c2adomainwithrimregulatessynapticvesicledockingandpriming
_version_	1718381671996194816

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming

Ejemplares similares