Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials

Jing Xie, Wuquan Deng Department of Endocrinology and Nephrology, Chongqing Emergency Medical Center, the Fourth People’s Hospital of Chongqing, Chongqing, China Background: The efficacy of psychosocial intervention has been proven in treatment of diabetic patients with depression in som...

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Autores principales:	Xie J, Deng W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	psychosocial intervention diabetes depression meta-analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/52a8f51f528d49ef83c19332b8d37af9
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spelling	oai:doaj.org-article:52a8f51f528d49ef83c19332b8d37af92021-12-02T01:06:53ZPsychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials1178-2021https://doaj.org/article/52a8f51f528d49ef83c19332b8d37af92017-10-01T00:00:00Zhttps://www.dovepress.com/psychosocial-intervention-for-patients-with-type-2-diabetes-mellitus-a-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Jing Xie, Wuquan Deng Department of Endocrinology and Nephrology, Chongqing Emergency Medical Center, the Fourth People’s Hospital of Chongqing, Chongqing, China Background: The efficacy of psychosocial intervention has been proven in treatment of diabetic patients with depression in some studies. This meta-analysis was conducted to explore the efficacy as well as additional effects of this method during diabetic management in patients with type 2 diabetes mellitus (T2DM) and comorbid depression.Methods: Electronic databases were searched from March 2000 to March 2017 for randomized controlled trials (RCTs) studying the effects of psychosocial intervention on T2DM patients with depression. There was no language limitation. Outcome measurements were symptoms of depression and anxiety, as well as glycemic control. A random effects model was conducted.Results: In total, 31 RCTs composed of 2,616 patients were eligible for this analysis. The psychosocial intervention was effective for depression symptoms with pooled standardized mean difference (SMD) of –1.50 (95% CI =–1.83, –1.18) and anxiety symptoms with SMD of –1.18 (95% CI =–1.50, –0.85). Meanwhile, the additional effects indicated a better improvement of glycemic control, including the fasting blood-glucose with SMD of –0.93 (95% CI =–1.15, –0.71), 2-hour postprandial plasma glucose with SMD of –0.84 (95% CI =–1.13, –0.56), and hemoglobin A1c with SMD of –0.81 (95% CI =–1.10, –0.53).Conclusion: These results demonstrate that the psychosocial intervention is very effective in treating T2DM patients with depression. Keywords: psychosocial intervention, type 2 diabetes mellitus, depression, meta-analysisXie JDeng WDove Medical Pressarticlepsychosocial interventiondiabetesdepressionmeta-analysisNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 2681-2690 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	psychosocial intervention diabetes depression meta-analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	psychosocial intervention diabetes depression meta-analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Xie J Deng W Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
description	Jing Xie, Wuquan Deng Department of Endocrinology and Nephrology, Chongqing Emergency Medical Center, the Fourth People’s Hospital of Chongqing, Chongqing, China Background: The efficacy of psychosocial intervention has been proven in treatment of diabetic patients with depression in some studies. This meta-analysis was conducted to explore the efficacy as well as additional effects of this method during diabetic management in patients with type 2 diabetes mellitus (T2DM) and comorbid depression.Methods: Electronic databases were searched from March 2000 to March 2017 for randomized controlled trials (RCTs) studying the effects of psychosocial intervention on T2DM patients with depression. There was no language limitation. Outcome measurements were symptoms of depression and anxiety, as well as glycemic control. A random effects model was conducted.Results: In total, 31 RCTs composed of 2,616 patients were eligible for this analysis. The psychosocial intervention was effective for depression symptoms with pooled standardized mean difference (SMD) of –1.50 (95% CI =–1.83, –1.18) and anxiety symptoms with SMD of –1.18 (95% CI =–1.50, –0.85). Meanwhile, the additional effects indicated a better improvement of glycemic control, including the fasting blood-glucose with SMD of –0.93 (95% CI =–1.15, –0.71), 2-hour postprandial plasma glucose with SMD of –0.84 (95% CI =–1.13, –0.56), and hemoglobin A1c with SMD of –0.81 (95% CI =–1.10, –0.53).Conclusion: These results demonstrate that the psychosocial intervention is very effective in treating T2DM patients with depression. Keywords: psychosocial intervention, type 2 diabetes mellitus, depression, meta-analysis
format	article
author	Xie J Deng W
author_facet	Xie J Deng W
author_sort	Xie J
title	Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
title_short	Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
title_full	Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
title_fullStr	Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
title_full_unstemmed	Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
title_sort	psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/52a8f51f528d49ef83c19332b8d37af9
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_version_	1718403315321012224

Psychosocial intervention for patients with type 2 diabetes mellitus and comorbid depression: a meta-analysis of randomized controlled trials

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