PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation

The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.

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Autores principales: Seul Kim, Nam Hyun Kim, Ji Eun Park, Jee Won Hwang, Nayeon Myung, Ki-Tae Hwang, Young A Kim, Chang-Young Jang, Yong Kee Kim
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/52a9c7201c7749b99216d7854cd4a940
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spelling oai:doaj.org-article:52a9c7201c7749b99216d7854cd4a9402021-12-02T15:34:12ZPRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation10.1038/s41467-020-14511-w2041-1723https://doaj.org/article/52a9c7201c7749b99216d7854cd4a9402020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14511-whttps://doaj.org/toc/2041-1723The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.Seul KimNam Hyun KimJi Eun ParkJee Won HwangNayeon MyungKi-Tae HwangYoung A KimChang-Young JangYong Kee KimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Seul Kim
Nam Hyun Kim
Ji Eun Park
Jee Won Hwang
Nayeon Myung
Ki-Tae Hwang
Young A Kim
Chang-Young Jang
Yong Kee Kim
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
description The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.
format article
author Seul Kim
Nam Hyun Kim
Ji Eun Park
Jee Won Hwang
Nayeon Myung
Ki-Tae Hwang
Young A Kim
Chang-Young Jang
Yong Kee Kim
author_facet Seul Kim
Nam Hyun Kim
Ji Eun Park
Jee Won Hwang
Nayeon Myung
Ki-Tae Hwang
Young A Kim
Chang-Young Jang
Yong Kee Kim
author_sort Seul Kim
title PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
title_short PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
title_full PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
title_fullStr PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
title_full_unstemmed PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
title_sort prmt6-mediated h3r2me2a guides aurora b to chromosome arms for proper chromosome segregation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/52a9c7201c7749b99216d7854cd4a940
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