PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.
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Nature Portfolio
2020
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oai:doaj.org-article:52a9c7201c7749b99216d7854cd4a9402021-12-02T15:34:12ZPRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation10.1038/s41467-020-14511-w2041-1723https://doaj.org/article/52a9c7201c7749b99216d7854cd4a9402020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14511-whttps://doaj.org/toc/2041-1723The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.Seul KimNam Hyun KimJi Eun ParkJee Won HwangNayeon MyungKi-Tae HwangYoung A KimChang-Young JangYong Kee KimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Seul Kim Nam Hyun Kim Ji Eun Park Jee Won Hwang Nayeon Myung Ki-Tae Hwang Young A Kim Chang-Young Jang Yong Kee Kim PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
description |
The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex. |
format |
article |
author |
Seul Kim Nam Hyun Kim Ji Eun Park Jee Won Hwang Nayeon Myung Ki-Tae Hwang Young A Kim Chang-Young Jang Yong Kee Kim |
author_facet |
Seul Kim Nam Hyun Kim Ji Eun Park Jee Won Hwang Nayeon Myung Ki-Tae Hwang Young A Kim Chang-Young Jang Yong Kee Kim |
author_sort |
Seul Kim |
title |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
title_short |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
title_full |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
title_fullStr |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
title_full_unstemmed |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation |
title_sort |
prmt6-mediated h3r2me2a guides aurora b to chromosome arms for proper chromosome segregation |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/52a9c7201c7749b99216d7854cd4a940 |
work_keys_str_mv |
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1718386899005997056 |