Circadian control of brain glymphatic and lymphatic fluid flow

Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution.

Guardado en:
Detalles Bibliográficos
Autores principales: Lauren M. Hablitz, Virginia Plá, Michael Giannetto, Hanna S. Vinitsky, Frederik Filip Stæger, Tanner Metcalfe, Rebecca Nguyen, Abdellatif Benrais, Maiken Nedergaard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/52b023d7976d45dea43058d42e720d90
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:52b023d7976d45dea43058d42e720d90
record_format dspace
spelling oai:doaj.org-article:52b023d7976d45dea43058d42e720d902021-12-02T19:09:31ZCircadian control of brain glymphatic and lymphatic fluid flow10.1038/s41467-020-18115-22041-1723https://doaj.org/article/52b023d7976d45dea43058d42e720d902020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18115-2https://doaj.org/toc/2041-1723Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution.Lauren M. HablitzVirginia PláMichael GiannettoHanna S. VinitskyFrederik Filip StægerTanner MetcalfeRebecca NguyenAbdellatif BenraisMaiken NedergaardNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lauren M. Hablitz
Virginia Plá
Michael Giannetto
Hanna S. Vinitsky
Frederik Filip Stæger
Tanner Metcalfe
Rebecca Nguyen
Abdellatif Benrais
Maiken Nedergaard
Circadian control of brain glymphatic and lymphatic fluid flow
description Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution.
format article
author Lauren M. Hablitz
Virginia Plá
Michael Giannetto
Hanna S. Vinitsky
Frederik Filip Stæger
Tanner Metcalfe
Rebecca Nguyen
Abdellatif Benrais
Maiken Nedergaard
author_facet Lauren M. Hablitz
Virginia Plá
Michael Giannetto
Hanna S. Vinitsky
Frederik Filip Stæger
Tanner Metcalfe
Rebecca Nguyen
Abdellatif Benrais
Maiken Nedergaard
author_sort Lauren M. Hablitz
title Circadian control of brain glymphatic and lymphatic fluid flow
title_short Circadian control of brain glymphatic and lymphatic fluid flow
title_full Circadian control of brain glymphatic and lymphatic fluid flow
title_fullStr Circadian control of brain glymphatic and lymphatic fluid flow
title_full_unstemmed Circadian control of brain glymphatic and lymphatic fluid flow
title_sort circadian control of brain glymphatic and lymphatic fluid flow
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/52b023d7976d45dea43058d42e720d90
work_keys_str_mv AT laurenmhablitz circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT virginiapla circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT michaelgiannetto circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT hannasvinitsky circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT frederikfilipstæger circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT tannermetcalfe circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT rebeccanguyen circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT abdellatifbenrais circadiancontrolofbrainglymphaticandlymphaticfluidflow
AT maikennedergaard circadiancontrolofbrainglymphaticandlymphaticfluidflow
_version_ 1718377086382505984