Circadian control of brain glymphatic and lymphatic fluid flow
Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution.
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/52b023d7976d45dea43058d42e720d90 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:52b023d7976d45dea43058d42e720d90 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:52b023d7976d45dea43058d42e720d902021-12-02T19:09:31ZCircadian control of brain glymphatic and lymphatic fluid flow10.1038/s41467-020-18115-22041-1723https://doaj.org/article/52b023d7976d45dea43058d42e720d902020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18115-2https://doaj.org/toc/2041-1723Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution.Lauren M. HablitzVirginia PláMichael GiannettoHanna S. VinitskyFrederik Filip StægerTanner MetcalfeRebecca NguyenAbdellatif BenraisMaiken NedergaardNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Lauren M. Hablitz Virginia Plá Michael Giannetto Hanna S. Vinitsky Frederik Filip Stæger Tanner Metcalfe Rebecca Nguyen Abdellatif Benrais Maiken Nedergaard Circadian control of brain glymphatic and lymphatic fluid flow |
description |
Glymphatic function is increased during the rest phase while more cerebrospinal fluid (CSF) drains directly to the lymphatic system during the active phase. The water channel aquaporin-4 supports these endogenous, circadian rhythms in CSF distribution. |
format |
article |
author |
Lauren M. Hablitz Virginia Plá Michael Giannetto Hanna S. Vinitsky Frederik Filip Stæger Tanner Metcalfe Rebecca Nguyen Abdellatif Benrais Maiken Nedergaard |
author_facet |
Lauren M. Hablitz Virginia Plá Michael Giannetto Hanna S. Vinitsky Frederik Filip Stæger Tanner Metcalfe Rebecca Nguyen Abdellatif Benrais Maiken Nedergaard |
author_sort |
Lauren M. Hablitz |
title |
Circadian control of brain glymphatic and lymphatic fluid flow |
title_short |
Circadian control of brain glymphatic and lymphatic fluid flow |
title_full |
Circadian control of brain glymphatic and lymphatic fluid flow |
title_fullStr |
Circadian control of brain glymphatic and lymphatic fluid flow |
title_full_unstemmed |
Circadian control of brain glymphatic and lymphatic fluid flow |
title_sort |
circadian control of brain glymphatic and lymphatic fluid flow |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/52b023d7976d45dea43058d42e720d90 |
work_keys_str_mv |
AT laurenmhablitz circadiancontrolofbrainglymphaticandlymphaticfluidflow AT virginiapla circadiancontrolofbrainglymphaticandlymphaticfluidflow AT michaelgiannetto circadiancontrolofbrainglymphaticandlymphaticfluidflow AT hannasvinitsky circadiancontrolofbrainglymphaticandlymphaticfluidflow AT frederikfilipstæger circadiancontrolofbrainglymphaticandlymphaticfluidflow AT tannermetcalfe circadiancontrolofbrainglymphaticandlymphaticfluidflow AT rebeccanguyen circadiancontrolofbrainglymphaticandlymphaticfluidflow AT abdellatifbenrais circadiancontrolofbrainglymphaticandlymphaticfluidflow AT maikennedergaard circadiancontrolofbrainglymphaticandlymphaticfluidflow |
_version_ |
1718377086382505984 |