Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers

Young women with reproductive tract neoplasms who receive treatment leading to termination of ovarian function often suffer from menopause symptoms that contribute to dramatic drop in quality of life. Climacteric symptoms in women with iatrogenic menopause are more severe than in case of natural men...

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Autores principales:	O. V. Shabalova, S. V. Yureneva, S. V. Khokhlova, Zh. R. Gardanova, E. I. Ermakova
Formato:	article
Lenguaje:	RU
Publicado:	IP Habib O.N. 2020
Materias:	tumors of reproductive system menopause menopause symptoms climacteric syndrome rehabilitation non-hormonal treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/52b9e89766084baa8bff62d4d69a125b
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spelling	oai:doaj.org-article:52b9e89766084baa8bff62d4d69a125b2021-11-30T17:03:34ZManaging menopausal symptoms in patients with hormone receptor-positive gynecologic cancers1815-14341815-144210.26442/18151434.2020.3.200104https://doaj.org/article/52b9e89766084baa8bff62d4d69a125b2020-11-01T00:00:00Zhttps://modernonco.orscience.ru/1815-1434/article/viewFile/52653/36092https://doaj.org/toc/1815-1434https://doaj.org/toc/1815-1442Young women with reproductive tract neoplasms who receive treatment leading to termination of ovarian function often suffer from menopause symptoms that contribute to dramatic drop in quality of life. Climacteric symptoms in women with iatrogenic menopause are more severe than in case of natural menopause, especially in women with reproductive tract neoplasms. They lead to dramatic drop in quality of life and are one of the main reasons to stop applying endocrine therapy in women with hormone-positive tumors, which leads to decrease in disease free survival and to decline the prognosis. The most effective treatment option for climacteric symptoms of moderate to severe degrees is menopause hormone therapy; however, such therapy is not suitable for patients with estrogen-dependent tumors in past medical history due to the likelihood risk of progression of cancer, as well as the risk of venous thrombosis, the frequency of which in cancer patients increases. Non-hormonal pharmacological and non-pharmacological correction methods are used as first-line therapy for menopause disorders in women with estrogen-dependent tumors of the reproductive system. Among non-hormonal non-pharmacological correction methods actively study such methods as acupuncture, yoga, exercise to control weight, and a diet rich in phytoestrogens. The most effective non-hormonal methods of correcting vasomotor symptoms are serotonin and norepinephrine reuptake inhibitors. However, currently in Russia these drugs can be prescribed only by a psychiatrist. The finding of effective and safe non-hormonal methods to correct menopause symptoms in women with hormone-positive reproductive tract tumors is the important task in practice among doctors in different specialties.O. V. ShabalovaS. V. YurenevaS. V. KhokhlovaZh. R. GardanovaE. I. ErmakovaIP Habib O.N.articletumors of reproductive systemmenopausemenopause symptomsclimacteric syndromerehabilitationnon-hormonal treatmentNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282RUСовременная онкология, Vol 22, Iss 3, Pp 154-159 (2020)
institution	DOAJ
collection	DOAJ
language	RU
topic	tumors of reproductive system menopause menopause symptoms climacteric syndrome rehabilitation non-hormonal treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	tumors of reproductive system menopause menopause symptoms climacteric syndrome rehabilitation non-hormonal treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 O. V. Shabalova S. V. Yureneva S. V. Khokhlova Zh. R. Gardanova E. I. Ermakova Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
description	Young women with reproductive tract neoplasms who receive treatment leading to termination of ovarian function often suffer from menopause symptoms that contribute to dramatic drop in quality of life. Climacteric symptoms in women with iatrogenic menopause are more severe than in case of natural menopause, especially in women with reproductive tract neoplasms. They lead to dramatic drop in quality of life and are one of the main reasons to stop applying endocrine therapy in women with hormone-positive tumors, which leads to decrease in disease free survival and to decline the prognosis. The most effective treatment option for climacteric symptoms of moderate to severe degrees is menopause hormone therapy; however, such therapy is not suitable for patients with estrogen-dependent tumors in past medical history due to the likelihood risk of progression of cancer, as well as the risk of venous thrombosis, the frequency of which in cancer patients increases. Non-hormonal pharmacological and non-pharmacological correction methods are used as first-line therapy for menopause disorders in women with estrogen-dependent tumors of the reproductive system. Among non-hormonal non-pharmacological correction methods actively study such methods as acupuncture, yoga, exercise to control weight, and a diet rich in phytoestrogens. The most effective non-hormonal methods of correcting vasomotor symptoms are serotonin and norepinephrine reuptake inhibitors. However, currently in Russia these drugs can be prescribed only by a psychiatrist. The finding of effective and safe non-hormonal methods to correct menopause symptoms in women with hormone-positive reproductive tract tumors is the important task in practice among doctors in different specialties.
format	article
author	O. V. Shabalova S. V. Yureneva S. V. Khokhlova Zh. R. Gardanova E. I. Ermakova
author_facet	O. V. Shabalova S. V. Yureneva S. V. Khokhlova Zh. R. Gardanova E. I. Ermakova
author_sort	O. V. Shabalova
title	Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
title_short	Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
title_full	Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
title_fullStr	Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
title_full_unstemmed	Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
title_sort	managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers
publisher	IP Habib O.N.
publishDate	2020
url	https://doaj.org/article/52b9e89766084baa8bff62d4d69a125b
work_keys_str_mv	AT ovshabalova managingmenopausalsymptomsinpatientswithhormonereceptorpositivegynecologiccancers AT svyureneva managingmenopausalsymptomsinpatientswithhormonereceptorpositivegynecologiccancers AT svkhokhlova managingmenopausalsymptomsinpatientswithhormonereceptorpositivegynecologiccancers AT zhrgardanova managingmenopausalsymptomsinpatientswithhormonereceptorpositivegynecologiccancers AT eiermakova managingmenopausalsymptomsinpatientswithhormonereceptorpositivegynecologiccancers
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Managing menopausal symptoms in patients with hormone receptor-positive gynecologic cancers

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