Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants

BACKGROUND AND OBJECTIVE: Jaundice (hyperbilirubinemia) is one of the most common clinical complaints during infancy among term and premature infants during the first week of life. Phototherapy is an effective and accepted treatment for neonatal hyperbilirubinemia, which may be associated with compl...

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Autores principales:	M Habibi, A Karbord, M Vahidi, F Samiee Rad
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2021
Materias:	infant unconjugated hyperbilirubinemia phototherapy calcium oral treatment. Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/52c40ebcb33f4b8ea8762ef4e0eb2b59
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spelling	oai:doaj.org-article:52c40ebcb33f4b8ea8762ef4e0eb2b592021-11-29T07:40:49ZComparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants1561-41072251-7170https://doaj.org/article/52c40ebcb33f4b8ea8762ef4e0eb2b592021-03-01T00:00:00Zhttp://jbums.org/article-1-9552-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Jaundice (hyperbilirubinemia) is one of the most common clinical complaints during infancy among term and premature infants during the first week of life. Phototherapy is an effective and accepted treatment for neonatal hyperbilirubinemia, which may be associated with complications such as skin, eye and electrolyte disorders. This study was performed to compare the effect of phototherapy with oral calcium versus phototherapy alone in the treatment of unconjugated hyperbilirubinemia in healthy term infants. METHODS: This clinical trial study was performed on 50 healthy term infants with jaundice (serum bilirubin 6.9-21 mg/dL). Neonates were randomly divided into intervention (50 mg/kg body weight of oral calcium with phototherapy) and control (phototherapy) groups. Data related to age, gender, birth weight, gestational age, number of hospitalization days and bilirubin level at the beginning of hospitalization and at 24, 48 and 72 hours were collected and compared in a checklist. FINDINGS: Decrease in total bilirubin level was observed with a significant difference between the two groups (p=0.000). The mean unconjugated hyperbilirubinemia showed significant difference in the intervention group (2.1±0.5 mg/dl) and the control group (2.6±1.3 mg/dl) (p=0.03). The changes in unconjugated hyperbilirubinemia in repeated measures was also significant in the intervention group (p=0.01). CONCLUSION: The results of the study showed that oral calcium with phototherapy may be effective in reducing neonatal jaundice.M HabibiA KarbordM VahidiF Samiee RadBabol University of Medical Sciencesarticleinfantunconjugated hyperbilirubinemiaphototherapycalciumoraltreatment.MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 23, Iss 1, Pp 70-75 (2021)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	infant unconjugated hyperbilirubinemia phototherapy calcium oral treatment. Medicine R Medicine (General) R5-920
spellingShingle	infant unconjugated hyperbilirubinemia phototherapy calcium oral treatment. Medicine R Medicine (General) R5-920 M Habibi A Karbord M Vahidi F Samiee Rad Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
description	BACKGROUND AND OBJECTIVE: Jaundice (hyperbilirubinemia) is one of the most common clinical complaints during infancy among term and premature infants during the first week of life. Phototherapy is an effective and accepted treatment for neonatal hyperbilirubinemia, which may be associated with complications such as skin, eye and electrolyte disorders. This study was performed to compare the effect of phototherapy with oral calcium versus phototherapy alone in the treatment of unconjugated hyperbilirubinemia in healthy term infants. METHODS: This clinical trial study was performed on 50 healthy term infants with jaundice (serum bilirubin 6.9-21 mg/dL). Neonates were randomly divided into intervention (50 mg/kg body weight of oral calcium with phototherapy) and control (phototherapy) groups. Data related to age, gender, birth weight, gestational age, number of hospitalization days and bilirubin level at the beginning of hospitalization and at 24, 48 and 72 hours were collected and compared in a checklist. FINDINGS: Decrease in total bilirubin level was observed with a significant difference between the two groups (p=0.000). The mean unconjugated hyperbilirubinemia showed significant difference in the intervention group (2.1±0.5 mg/dl) and the control group (2.6±1.3 mg/dl) (p=0.03). The changes in unconjugated hyperbilirubinemia in repeated measures was also significant in the intervention group (p=0.01). CONCLUSION: The results of the study showed that oral calcium with phototherapy may be effective in reducing neonatal jaundice.
format	article
author	M Habibi A Karbord M Vahidi F Samiee Rad
author_facet	M Habibi A Karbord M Vahidi F Samiee Rad
author_sort	M Habibi
title	Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
title_short	Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
title_full	Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
title_fullStr	Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
title_full_unstemmed	Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants
title_sort	comparison of the effect of phototherapy with oral calcium versus phototherapy alone in the treatment of unconjugated hyperbilirubinemia in healthy term infants
publisher	Babol University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/52c40ebcb33f4b8ea8762ef4e0eb2b59
work_keys_str_mv	AT mhabibi comparisonoftheeffectofphototherapywithoralcalciumversusphototherapyaloneinthetreatmentofunconjugatedhyperbilirubinemiainhealthyterminfants AT akarbord comparisonoftheeffectofphototherapywithoralcalciumversusphototherapyaloneinthetreatmentofunconjugatedhyperbilirubinemiainhealthyterminfants AT mvahidi comparisonoftheeffectofphototherapywithoralcalciumversusphototherapyaloneinthetreatmentofunconjugatedhyperbilirubinemiainhealthyterminfants AT fsamieerad comparisonoftheeffectofphototherapywithoralcalciumversusphototherapyaloneinthetreatmentofunconjugatedhyperbilirubinemiainhealthyterminfants
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Comparison of the Effect of Phototherapy with Oral Calcium Versus Phototherapy Alone in the Treatment of Unconjugated Hyperbilirubinemia in Healthy Term Infants

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