Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure

Abstract We aimed to clarify clinical implications of intrarenal hemodynamics assessed by intrarenal Doppler ultrasonography (IRD) and their prognostic impacts in heart failure (HF). We performed a prospective observational study, and examined IRD and measured interlobar renal artery velocity time i...

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Autores principales:	Akiomi Yoshihisa, Koichiro Watanabe, Yu Sato, Shinji Ishibashi, Mitsuko Matsuda, Yukio Yamadera, Yasuhiro Ichijo, Tetsuro Yokokawa, Tomofumi Misaka, Masayoshi Oikawa, Atsushi Kobayashi, Yasuchika Takeishi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/52c643f443154d55b3b622d5e8bc7fa1
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spelling	oai:doaj.org-article:52c643f443154d55b3b622d5e8bc7fa12021-12-02T13:34:11ZIntrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure10.1038/s41598-020-79351-62045-2322https://doaj.org/article/52c643f443154d55b3b622d5e8bc7fa12020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79351-6https://doaj.org/toc/2045-2322Abstract We aimed to clarify clinical implications of intrarenal hemodynamics assessed by intrarenal Doppler ultrasonography (IRD) and their prognostic impacts in heart failure (HF). We performed a prospective observational study, and examined IRD and measured interlobar renal artery velocity time integral (VTI) and intrarenal venous flow (IRVF) patterns (monophasic or non-monophasic pattern) to assess intrarenal hypoperfusion and congestion in HF patients (n = 341). Seven patients were excluded in VTI analysis due to unclear imaging. The patients were divided into groups based on (A) VTI: high VTI (VTI ≥ 14.0 cm, n = 231) or low VTI (VTI < 14.0 cm, n = 103); and (B) IRVF patterns: monophasic (n = 36) or non-monophasic (n = 305). We compared post-discharge cardiac event rate between the groups, and right-heart catheterization was performed in 166 patients. Cardiac index was lower in low VTI than in high VTI (P = 0.04), and right atrial pressure was higher in monophasic than in non-monophasic (P = 0.03). In the Kaplan–Meier analysis, cardiac event rate was higher in low VTI and monophasic groups (P < 0.01, respectively). In the Cox proportional hazard analysis, the combination of low VTI and a monophasic IRVF pattern was a predictor of cardiac events (P < 0.01). IRD imaging might be associated with cardiac output and right atrial pressure, and prognosis.Akiomi YoshihisaKoichiro WatanabeYu SatoShinji IshibashiMitsuko MatsudaYukio YamaderaYasuhiro IchijoTetsuro YokokawaTomofumi MisakaMasayoshi OikawaAtsushi KobayashiYasuchika TakeishiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Akiomi Yoshihisa Koichiro Watanabe Yu Sato Shinji Ishibashi Mitsuko Matsuda Yukio Yamadera Yasuhiro Ichijo Tetsuro Yokokawa Tomofumi Misaka Masayoshi Oikawa Atsushi Kobayashi Yasuchika Takeishi Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
description	Abstract We aimed to clarify clinical implications of intrarenal hemodynamics assessed by intrarenal Doppler ultrasonography (IRD) and their prognostic impacts in heart failure (HF). We performed a prospective observational study, and examined IRD and measured interlobar renal artery velocity time integral (VTI) and intrarenal venous flow (IRVF) patterns (monophasic or non-monophasic pattern) to assess intrarenal hypoperfusion and congestion in HF patients (n = 341). Seven patients were excluded in VTI analysis due to unclear imaging. The patients were divided into groups based on (A) VTI: high VTI (VTI ≥ 14.0 cm, n = 231) or low VTI (VTI < 14.0 cm, n = 103); and (B) IRVF patterns: monophasic (n = 36) or non-monophasic (n = 305). We compared post-discharge cardiac event rate between the groups, and right-heart catheterization was performed in 166 patients. Cardiac index was lower in low VTI than in high VTI (P = 0.04), and right atrial pressure was higher in monophasic than in non-monophasic (P = 0.03). In the Kaplan–Meier analysis, cardiac event rate was higher in low VTI and monophasic groups (P < 0.01, respectively). In the Cox proportional hazard analysis, the combination of low VTI and a monophasic IRVF pattern was a predictor of cardiac events (P < 0.01). IRD imaging might be associated with cardiac output and right atrial pressure, and prognosis.
format	article
author	Akiomi Yoshihisa Koichiro Watanabe Yu Sato Shinji Ishibashi Mitsuko Matsuda Yukio Yamadera Yasuhiro Ichijo Tetsuro Yokokawa Tomofumi Misaka Masayoshi Oikawa Atsushi Kobayashi Yasuchika Takeishi
author_facet	Akiomi Yoshihisa Koichiro Watanabe Yu Sato Shinji Ishibashi Mitsuko Matsuda Yukio Yamadera Yasuhiro Ichijo Tetsuro Yokokawa Tomofumi Misaka Masayoshi Oikawa Atsushi Kobayashi Yasuchika Takeishi
author_sort	Akiomi Yoshihisa
title	Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
title_short	Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
title_full	Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
title_fullStr	Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
title_full_unstemmed	Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
title_sort	intrarenal doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/52c643f443154d55b3b622d5e8bc7fa1
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Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure

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