Lipid peroxidation processes in women with chronic parenteral viral hepatitis

Increased percentage of incidence of chronic parenteral viral hepatitis in women is an negative sign. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in women of reproductive age with the chronic form of parenteral viral hepatitis depending o...

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Autor principal: M. A. Rashidova
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
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Acceso en línea:https://doaj.org/article/52e7405ecf264807a0638490daf2b3b1
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spelling oai:doaj.org-article:52e7405ecf264807a0638490daf2b3b12021-11-23T06:14:34ZLipid peroxidation processes in women with chronic parenteral viral hepatitis2541-94202587-959610.12737/article_590823a4635b74.82785203https://doaj.org/article/52e7405ecf264807a0638490daf2b3b12016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/190https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Increased percentage of incidence of chronic parenteral viral hepatitis in women is an negative sign. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in women of reproductive age with the chronic form of parenteral viral hepatitis depending on a degree of infection process activity. The study involved 44 women with chronic parenteral viral hepatitis (including 24 patients with minimum and low degrees of activity and 20 patients with moderate and high degrees of activity) and 28 healthy women of the same age. Spectrophotometric and fluorometric methods were used. Patients with minimum and low degrees of activity of chronic parenteral viral hepatitis had lower levels of diene conjugates - 22.6 % less, an increased TBA-reactive product level - 53.4 % less, reducing superoxide dismutase activity (21.2 %) compared with the control. In the group with moderate and high activities of chronic parenteral viral hepatitis TBA-reactive product level was increased by 2.3 times and superoxide dismutase activity was decreased by 20.7 % in comparison with the control. The chronic form of parenteral viral hepatitis was characterized by the series of metabolic disorders depending on the degree of inflammatory process activity. This requires a more careful approach to therapeutic and diagnostic activities.M. A. RashidovaScientific Сentre for Family Health and Human Reproduction Problemsarticlelipid peroxidationantioxidant protectionchronic viral hepatitiswomenreproductive ageScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 70-73 (2016)
institution DOAJ
collection DOAJ
language RU
topic lipid peroxidation
antioxidant protection
chronic viral hepatitis
women
reproductive age
Science
Q
spellingShingle lipid peroxidation
antioxidant protection
chronic viral hepatitis
women
reproductive age
Science
Q
M. A. Rashidova
Lipid peroxidation processes in women with chronic parenteral viral hepatitis
description Increased percentage of incidence of chronic parenteral viral hepatitis in women is an negative sign. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in women of reproductive age with the chronic form of parenteral viral hepatitis depending on a degree of infection process activity. The study involved 44 women with chronic parenteral viral hepatitis (including 24 patients with minimum and low degrees of activity and 20 patients with moderate and high degrees of activity) and 28 healthy women of the same age. Spectrophotometric and fluorometric methods were used. Patients with minimum and low degrees of activity of chronic parenteral viral hepatitis had lower levels of diene conjugates - 22.6 % less, an increased TBA-reactive product level - 53.4 % less, reducing superoxide dismutase activity (21.2 %) compared with the control. In the group with moderate and high activities of chronic parenteral viral hepatitis TBA-reactive product level was increased by 2.3 times and superoxide dismutase activity was decreased by 20.7 % in comparison with the control. The chronic form of parenteral viral hepatitis was characterized by the series of metabolic disorders depending on the degree of inflammatory process activity. This requires a more careful approach to therapeutic and diagnostic activities.
format article
author M. A. Rashidova
author_facet M. A. Rashidova
author_sort M. A. Rashidova
title Lipid peroxidation processes in women with chronic parenteral viral hepatitis
title_short Lipid peroxidation processes in women with chronic parenteral viral hepatitis
title_full Lipid peroxidation processes in women with chronic parenteral viral hepatitis
title_fullStr Lipid peroxidation processes in women with chronic parenteral viral hepatitis
title_full_unstemmed Lipid peroxidation processes in women with chronic parenteral viral hepatitis
title_sort lipid peroxidation processes in women with chronic parenteral viral hepatitis
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2016
url https://doaj.org/article/52e7405ecf264807a0638490daf2b3b1
work_keys_str_mv AT marashidova lipidperoxidationprocessesinwomenwithchronicparenteralviralhepatitis
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