G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial.

G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial.

<h4>Background</h4>The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and -regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis. It therefore appears as an attractiv...

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Autores principales: Thomas Duning, Hagen Schiffbauer, Tobias Warnecke, Siawoosh Mohammadi, Agnes Floel, Katja Kolpatzik, Harald Kugel, Armin Schneider, Stefan Knecht, Michael Deppe, Wolf Rüdiger Schäbitz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/52ef0f4b86ed42a0b1bdc021f4ef14d5
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