Genetic diversity among ancient Nordic populations.

Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the suc...

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Autores principales:	Linea Melchior, Niels Lynnerup, Hans R Siegismund, Toomas Kivisild, Jørgen Dissing
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/52f0c7be5c7747e9a2332c47818c7485
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spelling	oai:doaj.org-article:52f0c7be5c7747e9a2332c47818c74852021-11-18T06:36:31ZGenetic diversity among ancient Nordic populations.1932-620310.1371/journal.pone.0011898https://doaj.org/article/52f0c7be5c7747e9a2332c47818c74852010-07-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20689597/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the success rate varied substantially between sites; the highest rates were obtained with untouched, freshly excavated material, whereas heavy handling, archeological preservation and storage for many years influenced the ability to obtain authentic endogenic DNA. While the nucleotide diversity at two locations was similar to that among extant Danes, the diversity at four sites was considerably higher. This supports previous observations for ancient Britons. The overall occurrence of haplogroups did not deviate from extant Scandinavians, however, haplogroup I was significantly more frequent among the ancient Danes (average 13%) than among extant Danes and Scandinavians (approximately 2.5%) as well as among other ancient population samples reported. Haplogroup I could therefore have been an ancient Southern Scandinavian type "diluted" by later immigration events. Interestingly, the two Neolithic samples (4,200 YBP, Bell Beaker culture) that were typed were haplogroup U4 and U5a, respectively, and the single Bronze Age sample (3,300-3,500 YBP) was haplogroup U4. These two haplogroups have been associated with the Mesolithic populations of Central and Northern Europe. Therefore, at least for Southern Scandinavia, our findings do not support a possible replacement of a haplogroup U dominated hunter-gatherer population by a more haplogroup diverse Neolithic Culture.Linea MelchiorNiels LynnerupHans R SiegismundToomas KivisildJørgen DissingPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 5, Iss 7, p e11898 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Linea Melchior Niels Lynnerup Hans R Siegismund Toomas Kivisild Jørgen Dissing Genetic diversity among ancient Nordic populations.
description	Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the success rate varied substantially between sites; the highest rates were obtained with untouched, freshly excavated material, whereas heavy handling, archeological preservation and storage for many years influenced the ability to obtain authentic endogenic DNA. While the nucleotide diversity at two locations was similar to that among extant Danes, the diversity at four sites was considerably higher. This supports previous observations for ancient Britons. The overall occurrence of haplogroups did not deviate from extant Scandinavians, however, haplogroup I was significantly more frequent among the ancient Danes (average 13%) than among extant Danes and Scandinavians (approximately 2.5%) as well as among other ancient population samples reported. Haplogroup I could therefore have been an ancient Southern Scandinavian type "diluted" by later immigration events. Interestingly, the two Neolithic samples (4,200 YBP, Bell Beaker culture) that were typed were haplogroup U4 and U5a, respectively, and the single Bronze Age sample (3,300-3,500 YBP) was haplogroup U4. These two haplogroups have been associated with the Mesolithic populations of Central and Northern Europe. Therefore, at least for Southern Scandinavia, our findings do not support a possible replacement of a haplogroup U dominated hunter-gatherer population by a more haplogroup diverse Neolithic Culture.
format	article
author	Linea Melchior Niels Lynnerup Hans R Siegismund Toomas Kivisild Jørgen Dissing
author_facet	Linea Melchior Niels Lynnerup Hans R Siegismund Toomas Kivisild Jørgen Dissing
author_sort	Linea Melchior
title	Genetic diversity among ancient Nordic populations.
title_short	Genetic diversity among ancient Nordic populations.
title_full	Genetic diversity among ancient Nordic populations.
title_fullStr	Genetic diversity among ancient Nordic populations.
title_full_unstemmed	Genetic diversity among ancient Nordic populations.
title_sort	genetic diversity among ancient nordic populations.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/52f0c7be5c7747e9a2332c47818c7485
work_keys_str_mv	AT lineamelchior geneticdiversityamongancientnordicpopulations AT nielslynnerup geneticdiversityamongancientnordicpopulations AT hansrsiegismund geneticdiversityamongancientnordicpopulations AT toomaskivisild geneticdiversityamongancientnordicpopulations AT jørgendissing geneticdiversityamongancientnordicpopulations
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Genetic diversity among ancient Nordic populations.

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