Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms

Arsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Patricia De Francisco, Ana Martín-González, Daniel Rodriguez-Martín, Silvia Díaz
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	arsenic toxicity yeasts microalgae resistance mechanisms Medicine R
Acceso en línea:	https://doaj.org/article/52fffd0d587b40d5a7676a64cdd9a818
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:52fffd0d587b40d5a7676a64cdd9a818
record_format	dspace
spelling	oai:doaj.org-article:52fffd0d587b40d5a7676a64cdd9a8182021-11-25T17:52:13ZInteractions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms10.3390/ijerph1822122261660-46011661-7827https://doaj.org/article/52fffd0d587b40d5a7676a64cdd9a8182021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/12226https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Arsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has induced the evolution of various genetic systems conferring useful capacities in many microorganisms to detoxify and even use arsenic, as an energy source. This review summarizes the microbial impact of the As biogeochemical cycle. Moreover, the poorly known adverse effects of this element on eukaryotic microbes, as well as the As uptake and detoxification mechanisms developed by yeast and protists, are discussed. Finally, an outlook of As microbial remediation makes evident the knowledge gaps and the necessity of new approaches to mitigate this environmental challenge.Patricia De FranciscoAna Martín-GonzálezDaniel Rodriguez-MartínSilvia DíazMDPI AGarticlearsenictoxicityyeastsmicroalgaeresistance mechanismsMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 12226, p 12226 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	arsenic toxicity yeasts microalgae resistance mechanisms Medicine R
spellingShingle	arsenic toxicity yeasts microalgae resistance mechanisms Medicine R Patricia De Francisco Ana Martín-González Daniel Rodriguez-Martín Silvia Díaz Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
description	Arsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has induced the evolution of various genetic systems conferring useful capacities in many microorganisms to detoxify and even use arsenic, as an energy source. This review summarizes the microbial impact of the As biogeochemical cycle. Moreover, the poorly known adverse effects of this element on eukaryotic microbes, as well as the As uptake and detoxification mechanisms developed by yeast and protists, are discussed. Finally, an outlook of As microbial remediation makes evident the knowledge gaps and the necessity of new approaches to mitigate this environmental challenge.
format	article
author	Patricia De Francisco Ana Martín-González Daniel Rodriguez-Martín Silvia Díaz
author_facet	Patricia De Francisco Ana Martín-González Daniel Rodriguez-Martín Silvia Díaz
author_sort	Patricia De Francisco
title	Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_short	Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_full	Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_fullStr	Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_full_unstemmed	Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_sort	interactions with arsenic: mechanisms of toxicity and cellular resistance in eukaryotic microorganisms
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/52fffd0d587b40d5a7676a64cdd9a818
work_keys_str_mv	AT patriciadefrancisco interactionswitharsenicmechanismsoftoxicityandcellularresistanceineukaryoticmicroorganisms AT anamartingonzalez interactionswitharsenicmechanismsoftoxicityandcellularresistanceineukaryoticmicroorganisms AT danielrodriguezmartin interactionswitharsenicmechanismsoftoxicityandcellularresistanceineukaryoticmicroorganisms AT silviadiaz interactionswitharsenicmechanismsoftoxicityandcellularresistanceineukaryoticmicroorganisms
_version_	1718411918856683520

Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms

Ejemplares similares