Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years

Thomas Gross,1 Sabrina Morell,1 Felix Amsler2 1Trauma Unit, Department of Surgery, Kantonsspital Aarau, Aarau, Switzerland; 2Amsler Consulting, Basel, Switzerland Aim: Against the background of conflicting data on the topic, this study aimed to determine the differences in longer-term patient outc...

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Autores principales:	Gross T, Morell S, Amsler F
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	major trauma longer-term outcome quality of life working capacity age Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/5306cb5f2bf8421d887b063b73b71b10
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spelling	oai:doaj.org-article:5306cb5f2bf8421d887b063b73b71b102021-12-02T01:13:03ZLonger-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years1178-1998https://doaj.org/article/5306cb5f2bf8421d887b063b73b71b102018-04-01T00:00:00Zhttps://www.dovepress.com/longer-term-quality-of-life-following-major-trauma-age-only-significan-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Thomas Gross,1 Sabrina Morell,1 Felix Amsler2 1Trauma Unit, Department of Surgery, Kantonsspital Aarau, Aarau, Switzerland; 2Amsler Consulting, Basel, Switzerland Aim: Against the background of conflicting data on the topic, this study aimed to determine the differences in longer-term patient outcomes following major trauma with regard to age.Materials and methods: A prospective trauma center survey of survivors of trauma (≥16 years) was carried out employing a New Injury Severity Score (NISS) ≥8 to investigate the influence of age on working capacity and several outcome scores, such as the trauma medical outcomes study Short Form-36 (physical component [PCS] and mental component [MCS]), the Euro Quality of Life (EuroQoL), or the Trauma Outcome Profile (TOP) at least 1 year following injury. Chi square tests, t-tests, and Pearson correlations were used as univariate; stepwise regression as multivariate analysis. Significance was set at p<0.05.Results: In all, 718 major trauma patients (53.4±19.4 years; NISS 18.4±9.2) participated in the study. Multivariate analysis showed only low associations of patient or trauma characteristics with longer-term outcome scores, highest for the Injury Severity Score of the extremities with the PCS (R2=0.08) or the working capacity of employed patients (n=383; R2=0.04). For age, overall associations were even lower (best with the PCS, R2=0.04) or could not be revealed at all (TOP or MCS). Subgroup analysis with regard to decennia revealed the age effect to be mainly attributable to patients aged ≥80, who presented with a significantly worse outcome compared to younger people in all overall and physical component scores ( p<0.001). In patients under 80 years an association of age was only found for EuroQoL (R2=0.01) and the PCS (R2=0.03).Conclusion: Given the small impact of age on the longer-term outcomes of major trauma patients, at least up to the age of 80 years, resuscitation as well as rehabilitation strategies should be adapted accordingly. Keywords: major trauma, longer term, outcome, quality of life, working capacity, age Gross TMorell SAmsler FDove Medical Pressarticlemajor traumalonger-termoutcomequality of lifeworking capacityageGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 13, Pp 773-785 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	major trauma longer-term outcome quality of life working capacity age Geriatrics RC952-954.6
spellingShingle	major trauma longer-term outcome quality of life working capacity age Geriatrics RC952-954.6 Gross T Morell S Amsler F Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
description	Thomas Gross,1 Sabrina Morell,1 Felix Amsler2 1Trauma Unit, Department of Surgery, Kantonsspital Aarau, Aarau, Switzerland; 2Amsler Consulting, Basel, Switzerland Aim: Against the background of conflicting data on the topic, this study aimed to determine the differences in longer-term patient outcomes following major trauma with regard to age.Materials and methods: A prospective trauma center survey of survivors of trauma (≥16 years) was carried out employing a New Injury Severity Score (NISS) ≥8 to investigate the influence of age on working capacity and several outcome scores, such as the trauma medical outcomes study Short Form-36 (physical component [PCS] and mental component [MCS]), the Euro Quality of Life (EuroQoL), or the Trauma Outcome Profile (TOP) at least 1 year following injury. Chi square tests, t-tests, and Pearson correlations were used as univariate; stepwise regression as multivariate analysis. Significance was set at p<0.05.Results: In all, 718 major trauma patients (53.4±19.4 years; NISS 18.4±9.2) participated in the study. Multivariate analysis showed only low associations of patient or trauma characteristics with longer-term outcome scores, highest for the Injury Severity Score of the extremities with the PCS (R2=0.08) or the working capacity of employed patients (n=383; R2=0.04). For age, overall associations were even lower (best with the PCS, R2=0.04) or could not be revealed at all (TOP or MCS). Subgroup analysis with regard to decennia revealed the age effect to be mainly attributable to patients aged ≥80, who presented with a significantly worse outcome compared to younger people in all overall and physical component scores ( p<0.001). In patients under 80 years an association of age was only found for EuroQoL (R2=0.01) and the PCS (R2=0.03).Conclusion: Given the small impact of age on the longer-term outcomes of major trauma patients, at least up to the age of 80 years, resuscitation as well as rehabilitation strategies should be adapted accordingly. Keywords: major trauma, longer term, outcome, quality of life, working capacity, age
format	article
author	Gross T Morell S Amsler F
author_facet	Gross T Morell S Amsler F
author_sort	Gross T
title	Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
title_short	Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
title_full	Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
title_fullStr	Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
title_full_unstemmed	Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
title_sort	longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/5306cb5f2bf8421d887b063b73b71b10
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Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years

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