Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia
Cardiac function fluctuates greatly across the day and night, but this is not simply a consequence of our changing behaviour. The authors highlight the role of the body’s circadian clock in regulating the heart electrical activity, including a time-of-day dependent susceptibility to cardiac arrhythm...
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Nature Portfolio
2021
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oai:doaj.org-article:530c60e952014c1cb2858a92a8c767752021-12-02T17:17:17ZDistinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia10.1038/s41467-021-22788-82041-1723https://doaj.org/article/530c60e952014c1cb2858a92a8c767752021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22788-8https://doaj.org/toc/2041-1723Cardiac function fluctuates greatly across the day and night, but this is not simply a consequence of our changing behaviour. The authors highlight the role of the body’s circadian clock in regulating the heart electrical activity, including a time-of-day dependent susceptibility to cardiac arrhythmias.Edward A. HayterSophie M. T. WehrensHans P. A. Van DongenAlessandra StangherlinShobhan GaddameedhiElena CrooksNichola J. BarronLuigi A. VenetucciJohn S. O’ NeillTimothy M. BrownDebra J. SkeneAndrew W. TraffordDavid A. BechtoldNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q |
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Science Q Edward A. Hayter Sophie M. T. Wehrens Hans P. A. Van Dongen Alessandra Stangherlin Shobhan Gaddameedhi Elena Crooks Nichola J. Barron Luigi A. Venetucci John S. O’ Neill Timothy M. Brown Debra J. Skene Andrew W. Trafford David A. Bechtold Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
description |
Cardiac function fluctuates greatly across the day and night, but this is not simply a consequence of our changing behaviour. The authors highlight the role of the body’s circadian clock in regulating the heart electrical activity, including a time-of-day dependent susceptibility to cardiac arrhythmias. |
format |
article |
author |
Edward A. Hayter Sophie M. T. Wehrens Hans P. A. Van Dongen Alessandra Stangherlin Shobhan Gaddameedhi Elena Crooks Nichola J. Barron Luigi A. Venetucci John S. O’ Neill Timothy M. Brown Debra J. Skene Andrew W. Trafford David A. Bechtold |
author_facet |
Edward A. Hayter Sophie M. T. Wehrens Hans P. A. Van Dongen Alessandra Stangherlin Shobhan Gaddameedhi Elena Crooks Nichola J. Barron Luigi A. Venetucci John S. O’ Neill Timothy M. Brown Debra J. Skene Andrew W. Trafford David A. Bechtold |
author_sort |
Edward A. Hayter |
title |
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
title_short |
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
title_full |
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
title_fullStr |
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
title_full_unstemmed |
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
title_sort |
distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/530c60e952014c1cb2858a92a8c76775 |
work_keys_str_mv |
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