Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery

Michael Müller, Katarzyna Pawlowicz, Myriam Böhm, Eva Hemkeppler, Christoph Lwowski, Lisa Hinzelmann, Mehdi Shajari, Thomas Kohnen Department of Ophthalmology, Goethe-University, Frankfurt, GermanyCorrespondence: Thomas KohnenDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, Frank...

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Autores principales:	Müller M, Pawlowicz K, Böhm M, Hemkeppler E, Lwowski C, Hinzelmann L, Shajari M, Kohnen T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	pseudoexfoliative syndrome effective lens position anterior depth changes cataract surgery Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/5310b75b5fc04a9ab6f7b5aab2c7fccc
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spelling	oai:doaj.org-article:5310b75b5fc04a9ab6f7b5aab2c7fccc2021-12-02T15:24:23ZImpact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery1177-5483https://doaj.org/article/5310b75b5fc04a9ab6f7b5aab2c7fccc2021-07-01T00:00:00Zhttps://www.dovepress.com/impact-of-pseudoexfoliative-syndrome-on-effective-lens-position-anteri-peer-reviewed-fulltext-article-OPTHhttps://doaj.org/toc/1177-5483Michael Müller, Katarzyna Pawlowicz, Myriam Böhm, Eva Hemkeppler, Christoph Lwowski, Lisa Hinzelmann, Mehdi Shajari, Thomas Kohnen Department of Ophthalmology, Goethe-University, Frankfurt, GermanyCorrespondence: Thomas KohnenDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, Frankfurt, 60590, GermanyTel +49 69 6301 3945Fax +49 69 6301 3893Email thomas.kohnen@kgu.dePurpose: To compare the effective lens position (ELP), anterior chamber depth (ACD) changes, and visual outcomes in patients with and without pseudoexfoliation syndrome (PEX) after cataract surgery.Design: Prospective, randomized, fellow-eye controlled clinical case series.Methods: This prospective comparative case series enrolled 56 eyes of 56 consecutive patients with (n = 28) or without PEX (n = 28) and clinically significant cataract who underwent standard phacoemulsification and were implanted with single-piece acrylic posterior chamber intraocular lenses (IOLs). The primary outcome parameters were the ACD referring to the distance between the corneal anterior surface and the lens anterior surface, which is an indicator of the postoperative axial position of the IOL (the so-called ELP) and distance corrected visual acuity (DCVA).Results: Before surgery, the ACD was 2.54 ± 0.42 mm in the PEX group and 2.53 ± 0.38 mm in the control group (p = 0.941). Postoperatively, the ACD was 4.29 ± 0.71 mm in the PEX group and 4.33 ± 0.72 mm in the normal group, respectively (p = 0.533). There was no significant difference in ACD changes between groups (PEX group: 1.75 ± 0.74 mm, control group: 1.81 ± 0.61 mm, p = 0.806) and DCVA pre- (p = 0.469) and postoperatively (PEX group: 0.11 ± 0.13 logMAR, control group: 0.09 ± 0.17 logMAR, p = 0.245) between groups.Conclusion: Preoperative and postoperative ACD, as an indicator of ELP, between PEX eyes and healthy eyes after cataract surgery showed no significant difference. Phacoemulsification induced similar changes in eyes with PEX compared to healthy eyes.Keywords: pseudoexfoliative syndrome, effective lens position, anterior chamber depth changes, cataract surgeryMüller MPawlowicz KBöhm MHemkeppler ELwowski CHinzelmann LShajari MKohnen TDove Medical Pressarticlepseudoexfoliative syndromeeffective lens positionanterior depth changescataract surgeryOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 2867-2873 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pseudoexfoliative syndrome effective lens position anterior depth changes cataract surgery Ophthalmology RE1-994
spellingShingle	pseudoexfoliative syndrome effective lens position anterior depth changes cataract surgery Ophthalmology RE1-994 Müller M Pawlowicz K Böhm M Hemkeppler E Lwowski C Hinzelmann L Shajari M Kohnen T Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
description	Michael Müller, Katarzyna Pawlowicz, Myriam Böhm, Eva Hemkeppler, Christoph Lwowski, Lisa Hinzelmann, Mehdi Shajari, Thomas Kohnen Department of Ophthalmology, Goethe-University, Frankfurt, GermanyCorrespondence: Thomas KohnenDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, Frankfurt, 60590, GermanyTel +49 69 6301 3945Fax +49 69 6301 3893Email thomas.kohnen@kgu.dePurpose: To compare the effective lens position (ELP), anterior chamber depth (ACD) changes, and visual outcomes in patients with and without pseudoexfoliation syndrome (PEX) after cataract surgery.Design: Prospective, randomized, fellow-eye controlled clinical case series.Methods: This prospective comparative case series enrolled 56 eyes of 56 consecutive patients with (n = 28) or without PEX (n = 28) and clinically significant cataract who underwent standard phacoemulsification and were implanted with single-piece acrylic posterior chamber intraocular lenses (IOLs). The primary outcome parameters were the ACD referring to the distance between the corneal anterior surface and the lens anterior surface, which is an indicator of the postoperative axial position of the IOL (the so-called ELP) and distance corrected visual acuity (DCVA).Results: Before surgery, the ACD was 2.54 ± 0.42 mm in the PEX group and 2.53 ± 0.38 mm in the control group (p = 0.941). Postoperatively, the ACD was 4.29 ± 0.71 mm in the PEX group and 4.33 ± 0.72 mm in the normal group, respectively (p = 0.533). There was no significant difference in ACD changes between groups (PEX group: 1.75 ± 0.74 mm, control group: 1.81 ± 0.61 mm, p = 0.806) and DCVA pre- (p = 0.469) and postoperatively (PEX group: 0.11 ± 0.13 logMAR, control group: 0.09 ± 0.17 logMAR, p = 0.245) between groups.Conclusion: Preoperative and postoperative ACD, as an indicator of ELP, between PEX eyes and healthy eyes after cataract surgery showed no significant difference. Phacoemulsification induced similar changes in eyes with PEX compared to healthy eyes.Keywords: pseudoexfoliative syndrome, effective lens position, anterior chamber depth changes, cataract surgery
format	article
author	Müller M Pawlowicz K Böhm M Hemkeppler E Lwowski C Hinzelmann L Shajari M Kohnen T
author_facet	Müller M Pawlowicz K Böhm M Hemkeppler E Lwowski C Hinzelmann L Shajari M Kohnen T
author_sort	Müller M
title	Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
title_short	Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
title_full	Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
title_fullStr	Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
title_full_unstemmed	Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery
title_sort	impact of pseudoexfoliative syndrome on effective lens position, anterior chamber depth changes, and visual outcome after cataract surgery
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/5310b75b5fc04a9ab6f7b5aab2c7fccc
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Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery

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