A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation

A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation

Endocytosis of T cell receptors (TCR) and their polarized recycling back to the plasma membrane is crucial for T cell activation; however, the underlying mechanisms remain unclear. Here the authors follow TCR and show that a mobile endocytic network connects clathrin-independent receptor endocytosis...

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Autores principales: Ewoud B. Compeer, Felix Kraus, Manuela Ecker, Gregory Redpath, Mayan Amiezer, Nils Rother, Philip R. Nicovich, Natasha Kapoor-Kaushik, Qiji Deng, Guerric P. B. Samson, Zhengmin Yang, Jieqiong Lou, Michael Carnell, Haig Vartoukian, Katharina Gaus, Jérémie Rossy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5315f8de18a145b38208d17d8b1c2fbf
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spelling oai:doaj.org-article:5315f8de18a145b38208d17d8b1c2fbf2021-12-02T15:34:41ZA mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation10.1038/s41467-018-04088-w2041-1723https://doaj.org/article/5315f8de18a145b38208d17d8b1c2fbf2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04088-whttps://doaj.org/toc/2041-1723Endocytosis of T cell receptors (TCR) and their polarized recycling back to the plasma membrane is crucial for T cell activation; however, the underlying mechanisms remain unclear. Here the authors follow TCR and show that a mobile endocytic network connects clathrin-independent receptor endocytosis to recycling which is required for T cell activation.Ewoud B. CompeerFelix KrausManuela EckerGregory RedpathMayan AmiezerNils RotherPhilip R. NicovichNatasha Kapoor-KaushikQiji DengGuerric P. B. SamsonZhengmin YangJieqiong LouMichael CarnellHaig VartoukianKatharina GausJérémie RossyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ewoud B. Compeer
Felix Kraus
Manuela Ecker
Gregory Redpath
Mayan Amiezer
Nils Rother
Philip R. Nicovich
Natasha Kapoor-Kaushik
Qiji Deng
Guerric P. B. Samson
Zhengmin Yang
Jieqiong Lou
Michael Carnell
Haig Vartoukian
Katharina Gaus
Jérémie Rossy
A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
description Endocytosis of T cell receptors (TCR) and their polarized recycling back to the plasma membrane is crucial for T cell activation; however, the underlying mechanisms remain unclear. Here the authors follow TCR and show that a mobile endocytic network connects clathrin-independent receptor endocytosis to recycling which is required for T cell activation.
format article
author Ewoud B. Compeer
Felix Kraus
Manuela Ecker
Gregory Redpath
Mayan Amiezer
Nils Rother
Philip R. Nicovich
Natasha Kapoor-Kaushik
Qiji Deng
Guerric P. B. Samson
Zhengmin Yang
Jieqiong Lou
Michael Carnell
Haig Vartoukian
Katharina Gaus
Jérémie Rossy
author_facet Ewoud B. Compeer
Felix Kraus
Manuela Ecker
Gregory Redpath
Mayan Amiezer
Nils Rother
Philip R. Nicovich
Natasha Kapoor-Kaushik
Qiji Deng
Guerric P. B. Samson
Zhengmin Yang
Jieqiong Lou
Michael Carnell
Haig Vartoukian
Katharina Gaus
Jérémie Rossy
author_sort Ewoud B. Compeer
title A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
title_short A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
title_full A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
title_fullStr A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
title_full_unstemmed A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
title_sort mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes t cell activation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5315f8de18a145b38208d17d8b1c2fbf
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