Molecular signature of high yield (growth) influenza a virus reassortants prepared as candidate vaccine seeds.
<h4>Background</h4>Human influenza virus isolates generally grow poorly in embryonated chicken eggs. Hence, gene reassortment of influenza A wild type (wt) viruses is performed with a highly egg adapted donor virus, A/Puerto Rico/8/1934 (PR8), to provide the high yield reassortant (HYR)...
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Autores principales: | , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Acceso en línea: | https://doaj.org/article/53196e23cc3f471daacefb07e938b4e1 |
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